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PEX1 Products

(Peroxisomal Biogenesis Factor 1 (PEX1))

Categories

This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. [provided by RefSeq, Jul 2008].

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Featured PEX1 Categories

PEX1 Antibodies

High quality antibodies with extensive validation data.

PEX1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PEX1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7163001
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN5014081
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN5014080
Quantity 100 μL
Datasheet Datasheet

Recommended PEX1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN418397
Quantity 96 tests
Datasheet Datasheet

Recommended PEX1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419214
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417897
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094488
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PEX1 products

Pedrosa, Francisco, Bicho, Dias, Barros-Barbosa, Hagmann, Dodt, Rodrigues, Azevedo: "Peroxisomal monoubiquitinated PEX5 interacts with the AAA ATPases PEX1 and PEX6 and is unfolded during its dislocation into the cytosol." in: The Journal of biological chemistry, Vol. 293, Issue 29, pp. 11553-11563, (2019) (PubMed).

Yik, Steinberg, Moser, Moser, Hacia: "Identification of novel mutations and sequence variation in the Zellweger syndrome spectrum of peroxisome biogenesis disorders." in: Human mutation, Vol. 30, Issue 3, pp. E467-80, (2009) (PubMed).

Collins, Gould: "Identification of a common PEX1 mutation in Zellweger syndrome." in: Human mutation, Vol. 14, Issue 1, pp. 45-53, (1999) (PubMed).

Geisbrecht, Collins, Reuber, Gould: "Disruption of a PEX1-PEX6 interaction is the most common cause of the neurologic disorders Zellweger syndrome, neonatal adrenoleukodystrophy, and infantile Refsum disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 15, pp. 8630-5, (1998) (PubMed).

Reuber, Germain-Lee, Collins, Morrell, Ameritunga, Moser, Valle, Gould: "Mutations in PEX1 are the most common cause of peroxisome biogenesis disorders." in: Nature genetics, Vol. 17, Issue 4, pp. 445-8, (1997) (PubMed).

Synonyms and alternative names related to PEX1

peroxisomal biogenesis factor 1 (PEX1), peroxisomal biogenesis factor 1 (Pex1), peroxisomal biogenesis factor 1 L homeolog (pex1.L), 5430414H02Rik, E330005K07Rik, PBD1A, PBD1B, pex1, RGD1559939, ZWS, ZWS1

Protein level used designations for PEX1

  • Zellweger syndrome
  • peroxin-1
  • peroxisome biogenesis disorder protein 1
  • peroxisome biogenesis factor 1
  • peroxisomal biogenesis factor 1 L homeolog
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