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Peroxiredoxin 3 Products

(Peroxiredoxin 3 (PRDX3))

Categories

This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured Peroxiredoxin 3 Categories

Peroxiredoxin 3 Antibodies

High quality antibodies with extensive validation data.

Peroxiredoxin 3 ELISA Kits

Reliable ELISA kits for a wide range of species.

Peroxiredoxin 3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Peroxiredoxin 3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (6)
Cat. No. ABIN524343
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7438094
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF, IP
Validations
  • (5)
Cat. No. ABIN7172023
Quantity 100 μg
Datasheet Datasheet

Recommended Peroxiredoxin 3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969222
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1161618
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1161617
Quantity 96 tests
Datasheet Datasheet

Recommended Peroxiredoxin 3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124363
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316153
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1692321
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Peroxiredoxin 3 products

Jin, Yang, Liang, Ding, Liang, Zhang, Wu, Yang, Liu, Huang, Shen, Tu, Pan, Wei, Yang, Zhou: "Compound kushen injection suppresses human acute myeloid leukaemia by regulating the Prdxs/ROS/Trx1 signalling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 277, (2019) (PubMed).

Zhao, Du, Zhou, Liu, Gu, Long: "Differences in Proinflammatory Property of Six Subtypes of Peroxiredoxins and Anti-Inflammatory Effect of Ligustilide in Macrophages." in: PLoS ONE, Vol. 11, Issue 10, pp. e0164586, (2016) (PubMed).

Gao, Liu, Chen, Lv, Wu, Mi, Wang: "Comparative study of Hsp27, GSK3?, Wnt1 and PRDX3 in Hirschsprung's disease." in: International journal of experimental pathology, Vol. 95, Issue 3, pp. 229-37, (2014) (PubMed).

Liu, Rong, Li, Liu, Wang, Li: "Vasectomy induces oxidative stress and up-regulates the expression of peroxiredoxins in mouse testis in short and early periods after surgery." in: The Journal of urology, Vol. 191, Issue 6, pp. 1920-6, (2014) (PubMed).

Kannan, Nguyen, Makarem, Dong, Shih, Eirew, Raouf, Emerman, Eaves: "Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 21, pp. 7789-94, (2014) (PubMed).

Peskin, Dickerhof, Poynton, Paton, Pace, Hampton, Winterbourn: "Hyperoxidation of peroxiredoxins 2 and 3: rate constants for the reactions of the sulfenic acid of the peroxidatic cysteine." in: The Journal of biological chemistry, Vol. 288, Issue 20, pp. 14170-7, (2013) (PubMed).

Goemaere, Knoops: "Peroxiredoxin distribution in the mouse brain with emphasis on neuronal populations affected in neurodegenerative disorders." in: The Journal of comparative neurology, Vol. 520, Issue 2, pp. 258-80, (2011) (PubMed).

Chang, Cho, Park, Yu, Kang, Rhee: "Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria." in: The Journal of biological chemistry, Vol. 279, Issue 40, pp. 41975-84, (2004) (PubMed).

Wood, Schröder, Robin Harris, Poole: "Structure, mechanism and regulation of peroxiredoxins." in: Trends in biochemical sciences, Vol. 28, Issue 1, pp. 32-40, (2003) (PubMed).

Rhee, Kang, Chang, Jeong, Kim: "Peroxiredoxin, a novel family of peroxidases." in: IUBMB life, Vol. 52, Issue 1-2, pp. 35-41, (2002) (PubMed).

Synonyms and alternative names related to Peroxiredoxin 3

peroxiredoxin 3 (prdx3), peroxiredoxin 3 (PRDX3), peroxiredoxin 3 S homeolog (prdx3.S), peroxiredoxin PRX3 (PRX3), peroxiredoxin 3 (Prdx3), AOP-1, AOP1, Aop1, AW822249, cb718, D0Tohi1, Ef2l, HBC189, MER5, Mer5, MGC83969, MTAP, PRDX3, PRO1748, prx-III, Prx3, SP-22, SP22, TDXM, wu:fk49e09, zgc:110282, zgc:112512

Protein level used designations for Peroxiredoxin 3

  • thioredoxin-dependent peroxide reductase, mitochondrial
  • peroxiredoxin 3
  • mitochondrial thioredoxin-dependent peroxide reductase
  • antioxidant protein 1
  • peroxiredoxin III
  • peroxiredoxin-3
  • protein MER5 homolog
  • AOP-1
  • Prx III
  • anti-oxidant protein 1
  • antioxidant protein
  • mitochondrial Trx dependent peroxide reductase
  • mitochondrial thioredoxin dependent peroxide reductase
  • perioredoxin-3
  • PRX-3
  • PRx III
  • 5'-methylthioadenosine phosphorylase
  • MTA phosphorylase
  • MTAPase
  • anti-oxidant like protein-1
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