PEPCK Products
(phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK))
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This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].
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Featured PEPCK Categories
PEPCK Antibodies
High quality antibodies with extensive validation data.
PEPCK ELISA Kits
Reliable ELISA kits for a wide range of species.
PEPCK Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PEPCK Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF, FACS
Validations
- (1)
- (6)
Cat. No.
ABIN185483
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (7)
Cat. No.
ABIN7193363
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, ICC
Validations
- (6)
Cat. No.
ABIN2855891
Quantity
100 μL
Datasheet
Datasheet
Recommended PEPCK ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969272
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958539
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1147906
Quantity
96 tests
Datasheet
Datasheet
Recommended PEPCK Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1314318
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7197336
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407928
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PEPCK products
: "A GTP-dependent Phosphoenolpyruvate Carboxykinase from Crassostrea gigas Involved in Immune Recognition." in: Developmental and comparative immunology, Vol. 77, pp. 318-329, (2018) (PubMed).: "Anti-phosphoenolpyruvate carboxykinase 2 antibody in patients with autoimmune hepatitis." in: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 44, Issue 9, pp. 1019-25, (2014) (PubMed).
: "PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis." in: Journal of hepatology, Vol. 59, Issue 1, pp. 105-13, (2013) (PubMed).
: "Light sensing in Aspergillus fumigatus highlights the case for establishing new models for fungal photobiology." in: mBio, Vol. 4, Issue 3, pp. e00260-13, (2013) (PubMed).
: "Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity." in: Diabetologia, Vol. 55, Issue 7, pp. 2032-43, (2012) (PubMed).
: "Expression of phosphoenolpyruvate carboxykinase gene in human adipose tissue: induction by rosiglitazone and genetic analyses of the adipocyte-specific region of the promoter in type 2 diabetes." in: Biochimie, Vol. 85, Issue 12, pp. 1257-64, (2004) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
Synonyms and alternative names related to PEPCK
phosphoenolpyruvate carboxykinase 2, mitochondrial (PCK2), phosphoenolpyruvate carboxykinase 2 (mitochondrial) (Pck2), phosphoenolpyruvate carboxykinase 2 (mitochondrial) (pck2), phosphoenolpyruvate carboxykinase 2, mitochondrial (Pck2), phosphoenolpyruvate carboxykinase 2 (mitochondrial) L homeolog (pck2.L), 1810010O14Rik, 9130022B02Rik, id:ibd5157, pck, pck2, pck2.S, PEPCK, PEPCK-M, PEPCK2, zgc:77867Protein level used designations for PEPCK
- PEP carboxykinase
- phosphoenolpyruvate carboxykinase [GTP], mitochondrial
- phosphoenolpyruvate carboxylase
- phosphopyruvate carboxylase
- mitochondrial phosphoenolpyruvate carboxykinase 2
- phosphoenolpyruvate carboxykinase 2 (mitochondrial) L homeolog
- phosphoenolpyruvate carboxykinase 2 (mitochondrial) S homeolog
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