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PELP1 Products

(Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))

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This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].

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Featured PELP1 Categories

PELP1 Antibodies

High quality antibodies with extensive validation data.

PELP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PELP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (13)
Cat. No. ABIN3023502
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN655815
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
Cat. No. ABIN5542538
Quantity 100 μL
Datasheet Datasheet

Recommended PELP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2565139
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PELP1 products

Yan, Sun, Wu, Wu, Hu, Sun, Liu, Ma, Liu, Xiao, Liu, Ning: "PELP1 Suppression Inhibits Gastric Cancer Through Downregulation of c-Src-PI3K-ERK Pathway." in: Frontiers in oncology, Vol. 9, pp. 1423, (2019) (PubMed).

Regan Anderson, Ma, Raj, Cidlowski, Helle, Knutson, Krutilina, Seagroves, Lange: "Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer." in: Cancer research, Vol. 76, Issue 6, pp. 1653-63, (2016) (PubMed).

Cortez, Mann, Tekmal, Suzuki, Miyata, Rodriguez-Aguayo, Lopez-Berestein, Sood, Vadlamudi: "Targeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancer." in: Breast cancer research : BCR, Vol. 14, Issue 4, pp. R108, (2014) (PubMed).

Fanis, Gillemans, Aghajanirefah, Pourfarzad, Demmers, Esteghamat, Vadlamudi, Grosveld, Philipsen, van Dijk: "Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 11, pp. 1263-73, (2012) (PubMed).

Habashy, Rakha, Aleskandarany, Ahmed, Green, Ellis, Powe: "FOXO3a nuclear localisation is associated with good prognosis in luminal-like breast cancer." in: Breast cancer research and treatment, Vol. 129, Issue 1, pp. 11-21, (2011) (PubMed).

Chakravarty, Roy, Babu, Dandamudi, Curiel, Vivas-Mejia, Lopez-Berestein, Sood, Vadlamudi: "Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2250-9, (2011) (PubMed).

Nair, Nair, Chakravarty, Challa, Manavathi, Yew, Kumar, Tekmal, Vadlamudi: "Cyclin-dependent kinase-mediated phosphorylation plays a critical role in the oncogenic functions of PELP1." in: Cancer research, Vol. 70, Issue 18, pp. 7166-75, (2010) (PubMed).

Rajhans, Nair, Nair, Cortez, Ikuko, Kirma, Zhou, Holden, Brann, Chen, Tekmal, Vadlamudi: "Modulation of in situ estrogen synthesis by proline-, glutamic acid-, and leucine-rich protein-1: potential estrogen receptor autocrine signaling loop in breast cancer cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 22, Issue 3, pp. 649-64, (2008) (PubMed).

Galluzzo, Ascenzi, Bulzomi, Marino: "The nutritional flavanone naringenin triggers antiestrogenic effects by regulating estrogen receptor alpha-palmitoylation." in: Endocrinology, Vol. 149, Issue 5, pp. 2567-75, (2008) (PubMed).

Nagpal, Nair, Chakravarty, Rajhans, Pothana, Brann, Tekmal, Vadlamudi: "Growth factor regulation of estrogen receptor coregulator PELP1 functions via Protein Kinase A pathway." in: Molecular cancer research : MCR, Vol. 6, Issue 5, pp. 851-61, (2008) (PubMed).

Synonyms and alternative names related to PELP1

proline, glutamate and leucine rich protein 1 (PELP1), proline, glutamate and leucine rich protein 1 (Pelp1), proline, glutamate and leucine rich protein 1 L homeolog (pelp1.L), proline, glutamic acid and leucine rich protein 1 (Pelp1), 4930563C04Rik, MNAR, P160, RGD1306320

Protein level used designations for PELP1

  • proline, glutamate and leucine rich protein 1
  • proline-, glutamic acid-, leucine-rich protein 1
  • proline, glutamic acid and leucine rich protein 1
  • proline, glutamic acid and leucine rich protein 1-like
  • modulator of non-genomic activity of estrogen receptor
  • proline and glutamic acid rich nuclear protein
  • proline-, glutamic acid- and leucine-rich protein 1
  • transcription factor HMX3
  • modulator of nongenomic activity of estrogen receptor
  • modulator of nongenomic actions of the estrogen receptor
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