PEG3 Products
(Paternally Expressed 3 (PEG3))
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In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2009].
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Featured PEG3 Categories
PEG3 Antibodies
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Recommended PEG3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (5)
Cat. No.
ABIN1490765
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (2)
- (2)
Cat. No.
ABIN735653
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6264130
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our PEG3 products
: "Laminin regulates PDGFRβ(+) cell stemness and muscle development." in: Nature communications, Vol. 7, pp. 11415, (2016) (PubMed).: "Diabetic uterus environment may play a key role in alterations of DNA methylation of several imprinted genes at mid-gestation in mice." in: Reproductive biology and endocrinology : RB&E, Vol. 11, Issue 1, pp. 119, (2014) (PubMed).
Synonyms and alternative names related to PEG3
paternally expressed 3 (PEG3), paternally expressed 3 (Peg3), paternally-expressed gene 3 protein (LOC100448879), AL022617, ASF-1, End4, Gcap4, mKIAA0287, PEG3, PW1, Pw1, Zfp102, ZKSCAN22, ZNF904, ZSCAN24Protein level used designations for PEG3
- Kruppel-type zinc finger protein
- paternally-expressed gene 3 protein
- zinc finger and SCAN domain-containing protein 24
- granule cell antiserum positive 4
- paternally expressed gene 3
- zinc-finger protein
- paternally expressed 3
- paternally-expressed gene 3 protein-like
- Paternally-expressed gene 3 protein
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