PEG10 Products
(Paternally Expressed 10 (PEG10))
Categories
This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. [provided by RefSeq, May 2010].
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Featured PEG10 Categories
PEG10 Antibodies
High quality antibodies with extensive validation data.
PEG10 ELISA Kits
Reliable ELISA kits for a wide range of species.
PEG10 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PEG10 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (6)
Cat. No.
ABIN1681320
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ICC
Validations
- (3)
- (3)
Cat. No.
ABIN969348
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN524962
Quantity
50 μg
Datasheet
Datasheet
Recommended PEG10 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969163
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6225627
Quantity
96 tests
Datasheet
Datasheet
Recommended PEG10 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314640
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094526
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3135926
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PEG10 products
: "ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis." in: Nature medicine, Vol. 24, Issue 12, pp. 1887-1898, (2019) (PubMed).: "DREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation." in: Nucleic acids research, Vol. 47, Issue 17, pp. 9087-9103, (2019) (PubMed).
: "PEG10 overexpression induced by E2F-1 promotes cell proliferation, migration, and invasion in pancreatic cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 30, (2017) (PubMed).
: "miR-122-mediated translational repression of PEG10 and its suppression in human hepatocellular carcinoma." in: Journal of translational medicine, Vol. 14, Issue 1, pp. 200, (2016) (PubMed).
: "uORFs, reinitiation and alternative translation start sites in human mRNAs." in: FEBS letters, Vol. 582, Issue 9, pp. 1293-7, (2008) (PubMed).
: "PEG10 directly regulated by E2Fs might have a role in the development of hepatocellular carcinoma." in: FEBS letters, Vol. 582, Issue 18, pp. 2793-8, (2008) (PubMed).
: "Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells." in: Oncogene, Vol. 26, Issue 39, pp. 5741-51, (2007) (PubMed).
Synonyms and alternative names related to PEG10
paternally expressed 10 (PEG10), paternally expressed 10 (Peg10), AA407948, EDR, Edr, HB-1, Mar2, Mart2, MEF3L, MyEF-3, RGAG3Protein level used designations for PEG10
- MEF3 like 1
- MEF3-like protein 1
- embryonal carcinoma differentiation regulated
- embryonal carcinoma differentiation-regulated protein
- mammalian retrotransposon-derived protein 2
- myelin expression factor 3-like protein 1
- paternally expressed gene 10 protein
- retrotransposon gag domain containing 3
- retrotransposon gag domain-containing protein 3
- retrotransposon-derived gag-like polyprotein
- retrotransposon-derived protein PEG10
- ty3/Gypsy-like protein
- MyEF-3 like
- embryonal carcinoma differentiation regulated protein
- myelin expression factor 3
- paternally expressed 10
- LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10
- retrotransposon-derived protein PEG10-like
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