PDZK1 Products
(PDZ Domain Containing 1 (PDZK1))
Categories
This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].
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Featured PDZK1 Categories
PDZK1 Antibodies
High quality antibodies with extensive validation data.
PDZK1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PDZK1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PDZK1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN562170
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN7269199
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (2)
Cat. No.
ABIN6264124
Quantity
100 μL
Datasheet
Datasheet
Recommended PDZK1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1144046
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1144047
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1144049
Quantity
96 tests
Datasheet
Datasheet
Recommended PDZK1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1314614
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5852951
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2131092
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PDZK1 products
: "Ouabain Regulates CFTR-Mediated Anion Secretion and Na,K-ATPase Transport in ADPKD Cells." in: The Journal of membrane biology, Vol. 248, Issue 6, pp. 1145-57, (2016) (PubMed).: "Mutation conferring apical-targeting motif on AE1 exchanger causes autosomal dominant distal RTA." in: Journal of the American Society of Nephrology : JASN, Vol. 23, Issue 7, pp. 1238-49, (2012) (PubMed).
: "The scavenger receptor class B, type I is a primary determinant of paraoxonase-1 association with high-density lipoproteins." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 30, Issue 11, pp. 2121-7, (2010) (PubMed).
: "A role for hepatic scavenger receptor class B, type I in decreasing high density lipoprotein levels in mice that lack phosphatidylethanolamine N-methyltransferase." in: The Journal of biological chemistry, Vol. 283, Issue 51, pp. 35496-506, (2008) (PubMed).
: "Catalytic mechanism of nitrile hydratase proposed by time-resolved X-ray crystallography using a novel substrate, tert-butylisonitrile." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36617-23, (2008) (PubMed).
: "Estrogen-regulated gene expression predicts response to endocrine therapy in patients with ovarian cancer." in: Gynecologic oncology, Vol. 106, Issue 3, pp. 461-8, (2007) (PubMed).
: "Fenofibrate induces a novel degradation pathway for scavenger receptor B-I independent of PDZK1." in: The Journal of biological chemistry, Vol. 280, Issue 24, pp. 23390-6, (2005) (PubMed).
: "Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface." in: The Journal of biological chemistry, Vol. 280, Issue 34, pp. 30143-9, (2005) (PubMed).
Synonyms and alternative names related to PDZK1
PDZ domain containing 1 (PDZK1), PDZ domain containing 1 L homeolog (pdzk1.L), PDZ domain containing 1 (pdzk1), PDZ domain containing 1 (Pdzk1), 1700023D20Rik, 2610507N21Rik, 4921513F16Rik, AI267131, AI314638, AL022680, CAP70, CLAMP, Clamp, D3Ertd537e, mPDZK1, NHERF-3, NHERF3, PDZD1, Pdzd1, PDZK1, xpdzk1Protein level used designations for PDZK1
- PDZ domain containing 1
- Na(+)/H(+) exchange regulatory cofactor NHE-RF3-like
- CFTR-associated protein of 70 kDa
- Na(+)/H(+) exchange regulatory cofactor NHE-RF3
- PDZ-containing kidney protein 1
- na/Pi cotransporter C-terminal-associated protein 1
- naPi-Cap1
- sodium-hydrogen exchanger regulatory factor 3
- NHERF-3
- Na(+)/H(+) exchanger regulatory factor 3
- PDZ domain-containing protein 1
- PDZK1-like protein
- C-terminal linking and modulating protein
- C-terminal-linking and modulating protein
- dietary Pi-regulated RNA-1
- diphor-1
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