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PDZD3 Products

(PDZ Domain Containing 3 (PDZD3))

Categories

Guanylyl cyclase C (GCC, or GUCY2C\; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR\; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).[supplied by OMIM, Mar 2008].

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Featured PDZD3 Categories

PDZD3 Antibodies

High quality antibodies with extensive validation data.

PDZD3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PDZD3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN529096
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7160813
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN949657
Quantity 100 μL
Datasheet Datasheet

Recommended PDZD3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314608
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3128056
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3084313
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PDZD3 products

Hovakimyan, Meyer, Lukas, Luo, Gudziol, Hummel, Rolfs, Wree, Witt: "Olfactory deficits in Niemann-Pick type C1 (NPC1) disease." in: PLoS ONE, Vol. 8, Issue 12, pp. e82216, (2014) (PubMed).

Synonyms and alternative names related to PDZD3

PDZ domain containing 3 (Pdzd3), PDZ domain containing 3b (pdzd3b), PDZ domain containing 3 (PDZD3), IKEPP, NaPi-Cap2, NHERF4, PDZK2, Pdzk2, RGD1559807, zgc:194812

Protein level used designations for PDZD3

  • Na(+)/H(+) exchange regulatory cofactor NHE-RF4
  • PDZ domain containing 3
  • NHERF-4
  • PDZ domain containing 2
  • PDZ domain-containing protein 2
  • PDZ domain-containing protein 3
  • intestinal and kidney enriched PDZ protein
  • intestinal and kidney-enriched PDZ protein
  • na/Pi cotransporter C-terminal-associated protein 2
  • naPi-Cap2
  • natrium-phosphate cotransporter IIa C-terminal-associated protein 2
  • sodium-hydrogen exchanger regulatory factor 4
  • sodium-phosphate cotransporter IIa C-terminal-associated protein 2
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