PDZD3 Products
(PDZ Domain Containing 3 (PDZD3))
Categories
Guanylyl cyclase C (GCC, or GUCY2C\; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR\; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).[supplied by OMIM, Mar 2008].
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Featured PDZD3 Categories
PDZD3 Antibodies
High quality antibodies with extensive validation data.
PDZD3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PDZD3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN529096
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7160813
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN949657
Quantity
100 μL
Datasheet
Datasheet
Recommended PDZD3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314608
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3128056
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3084313
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PDZD3 products
: "Olfactory deficits in Niemann-Pick type C1 (NPC1) disease." in: PLoS ONE, Vol. 8, Issue 12, pp. e82216, (2014) (PubMed).Synonyms and alternative names related to PDZD3
PDZ domain containing 3 (Pdzd3), PDZ domain containing 3b (pdzd3b), PDZ domain containing 3 (PDZD3), IKEPP, NaPi-Cap2, NHERF4, PDZK2, Pdzk2, RGD1559807, zgc:194812Protein level used designations for PDZD3
- Na(+)/H(+) exchange regulatory cofactor NHE-RF4
- PDZ domain containing 3
- NHERF-4
- PDZ domain containing 2
- PDZ domain-containing protein 2
- PDZ domain-containing protein 3
- intestinal and kidney enriched PDZ protein
- intestinal and kidney-enriched PDZ protein
- na/Pi cotransporter C-terminal-associated protein 2
- naPi-Cap2
- natrium-phosphate cotransporter IIa C-terminal-associated protein 2
- sodium-hydrogen exchanger regulatory factor 4
- sodium-phosphate cotransporter IIa C-terminal-associated protein 2
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