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PDPK1 Products

(3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))

Categories

Serine/threonine kinase required for embryonic development. Inhibits apoptosis. Acts in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and activating Akt1 and S6k. May be involved in axonal pathfinding and synaptogenesis, and in spermatogenesis.

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Featured PDPK1 Categories

PDPK1 Antibodies

High quality antibodies with extensive validation data.

PDPK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PDPK1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PDPK1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (6)
Cat. No. ABIN744668
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (7)
Cat. No. ABIN3022352
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (7)
Cat. No. ABIN5542259
Quantity 100 μL
Datasheet Datasheet

Recommended PDPK1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6953358
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380681
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4886243
Quantity 96 tests
Datasheet Datasheet

Recommended PDPK1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
Cat. No. ABIN1314576
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121616
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121615
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our PDPK1 products

Pan, Strickland, Madhu, Johnson, Chand, Brody, Fertala, Zheng, Shapiro, Risbud: "RNA binding protein HuR regulates extracellular matrix gene expression and pH homeostasis independent of controlling HIF-1α signaling in nucleus pulposus cells." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 77, pp. 23-40, (2019) (PubMed).

Yanes, Zhang, Shen, Weyand, Goronzy: "Metabolic reprogramming in memory CD4 T cell responses of old adults." in: Clinical immunology (Orlando, Fla.), Vol. 207, pp. 58-67, (2019) (PubMed).

Li, Zhao, Qi, Wang, Zhang, Li, Qin: "lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma." in: International journal of oncology, Vol. 53, Issue 2, pp. 551-566, (2018) (PubMed).

Zhang, Yu, Chu, Wang, Xiong, Cai, Liu, Gao, Tao, Li, Li, Liang, Yang: "Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis." in: Molecular cell, Vol. 71, Issue 2, pp. 201-215.e7, (2018) (PubMed).

Tang, Yang, Wang, Gu, Xia, Feng, Yang, Zhao, Su, Su, Wang: "Nucleoside reverse transcriptase inhibitor-induced rat oocyte dysfunction and low fertility mediated by autophagy." in: Oncotarget, Vol. 9, Issue 3, pp. 3895-3907, (2018) (PubMed).

Gibier, Hémon, Fanchon, Gaudelot, Pottier, Ringot, Van Seuningen, Glowacki, Cauffiez, Blum, Copin, Perrais, Gnemmi: "Dual role of MUC1 mucin in kidney ischemia-reperfusion injury: Nephroprotector in early phase, but pro-fibrotic in late phase." in: Biochimica et biophysica acta, Vol. 1863, Issue 6, pp. 1336-1349, (2017) (PubMed).

Schmidt, Loos, Jin, Schmiech, Schmidt, Gaafary, Syrovets, Simmet: "Acetyl-lupeolic acid inhibits Akt signaling and induces apoptosis in chemoresistant prostate cancer cellsin vitroandin vivo." in: Oncotarget, Vol. 8, Issue 33, pp. 55147-55161, (2017) (PubMed).

Qin, Zheng, Zhou, Ou, Huang, Yan, Qin, Yang, Su, Bai, Guo, Lin: "Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins." in: Scientific reports, Vol. 6, pp. 19587, (2017) (PubMed).

Sung, Chen, Liao, Lee: "Enhanced aerobic glycolysis of nasopharyngeal carcinoma cells by Epstein-Barr virus latent membrane protein 1." in: Experimental cell research, Vol. 359, Issue 1, pp. 94-100, (2017) (PubMed).

Lin, Lin, Kang, Liu, Wang, Zheng, Yu, Lin: "Similar PDK1-AKT-mTOR pathway activation in balloon cells and dysmorphic neurons of type II focal cortical dysplasia with refractory epilepsy." in: Epilepsy research, Vol. 112, pp. 137-49, (2015) (PubMed).

Synonyms and alternative names related to PDPK1

3-phosphoinositide dependent protein kinase 1 (PDPK1), 3-phosphoinositide dependent protein kinase 1 L homeolog (pdpk1.L), 3-phosphoinositide dependent protein kinase 1 (pdpk1), 3-phosphoinositide dependent protein kinase-1 (Pdpk1), 3-phosphoinositide dependent protein kinase 1 (Pdpk1), 3-phosphoinositide dependent protein kinase 1a (pdpk1a), 3-phosphoinositide-dependent protein kinase 1 (LOC100380750), 3-phosphoinositide-dependent protein kinase 1 (pdk-1), 3'-phosphoinositide-dependent protein kinase 1 (PDK1), 3-phosphoinositide dependent protein kinase 1b (pdpk1b), 3'-phosphoinositide-dependent protein kinase 1, 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1, ATPDK1, AtPDK1, MGC82080, PDK1, Pdk1, pdpk1, PDPK2, PRO0461, T32M21.110, T32M21_110, zgc:77318, zgc:153787

Protein level used designations for PDPK1

  • 3-phosphoinositide-dependent protein kinase 1
  • 3-phosphoinositide dependent protein kinase-1
  • pkB kinase
  • protein kinase B kinase
  • PkB kinase like gene 1
  • Pkb kinase
  • mPDK1
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