PDK2 Products
(Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
Categories
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].
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Featured PDK2 Categories
PDK2 Antibodies
High quality antibodies with extensive validation data.
PDK2 ELISA Kits
Reliable ELISA kits for a wide range of species.
PDK2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PDK2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), RNAi
Validations
- (4)
- (6)
Cat. No.
ABIN562160
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, ICC, IP
Validations
- (6)
Cat. No.
ABIN7439423
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (5)
Cat. No.
ABIN5542665
Quantity
100 μL
Datasheet
Datasheet
Recommended PDK2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959010
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6231784
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5658317
Quantity
96 tests
Datasheet
Datasheet
Recommended PDK2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314551
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314549
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509069
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PDK2 products
: "PDK2 induces cisplatin-resistance in lung adenocarcinoma via transcriptional regulation of CNNM3." in: Journal of drug targeting, Vol. 27, Issue 4, pp. 460-465, (2019) (PubMed).: "Selective Phosphorylation Inhibitor of Delta Protein Kinase C-Pyruvate Dehydrogenase Kinase Protein-Protein Interactions: Application for Myocardial Injury in Vivo." in: Journal of the American Chemical Society, Vol. 138, Issue 24, pp. 7626-35, (2018) (PubMed).
: "Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death." in: The Journal of biological chemistry, Vol. 291, Issue 26, pp. 13608-21, (2016) (PubMed).
: "Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined 13C Hyperpolarized Magnetic Resonance and Echocardiography Study." in: Diabetes, Vol. 64, Issue 8, pp. 2735-43, (2015) (PubMed).
: "Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation." in: Journal of cell science, Vol. 128, Issue 13, pp. 2319-29, (2015) (PubMed).
: "Retinoic acid-related orphan receptor alpha reprograms glucose metabolism in glutamine-deficient hepatoma cells." in: Hepatology (Baltimore, Md.), Vol. 61, Issue 3, pp. 953-64, (2015) (PubMed).
: "Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 35153-60, (2012) (PubMed).
: "p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2." in: Cancer research, Vol. 72, Issue 2, pp. 560-7, (2012) (PubMed).
: "Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPAR?-independent mechanisms." in: European journal of cell biology, Vol. 90, Issue 8, pp. 657-64, (2011) (PubMed).
: "The relationship between human skeletal muscle pyruvate dehydrogenase phosphatase activity and muscle aerobic capacity." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 111, Issue 2, pp. 427-34, (2011) (PubMed).
Synonyms and alternative names related to PDK2
pyruvate dehydrogenase kinase 2 (PDK2), pyruvate dehydrogenase kinase, isoenzyme 2 (Pdk2), pyruvate dehydrogenase kinase 2 (Pdk2), pyruvate dehydrogenase kinase, isozyme 2b (pdk2b), PDHK2, Pdk, PDK2, PDKII, zgc:56209Protein level used designations for PDK2
- PDH kinase 2
- pyruvate dehydrogenase kinase, isoenzyme 2
- pyruvate dehydrogenase, lipoamide, kinase isozyme 2, mitochondrial
- [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial
- pyruvate dehydrogenase 2
- pyruvate dehydrogenase kinase, isozyme 2
- PDK P45
- pyruvate dehydrogenase kinase 2 subunit p45 (PDK2)
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