PDHE1-B Antibodies
(Pyruvate Dehydrogenase E1 beta Subunit (PDHE1-B))
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012].
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Recommended PDHE1-B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ICC, IF, IHC (p), WB
Validations
- (5)
Cat. No.
ABIN2855755
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
Validations
Cat. No.
ABIN6901241
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
Validations
Cat. No.
ABIN6869115
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our PDHE1-B products
: "Targeting thiamine-dependent enzymes for metabolic therapies in oral squamous cell carcinoma?" in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, Vol. 18, Issue 2, pp. 196-205, (2016) (PubMed).: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
Synonyms and alternative names related to PDHE1-B
pyruvate dehydrogenase E1 beta subunit (PDHB), pyruvate dehydrogenase E1 beta subunit (Pdhb), PDHBD, PDHE1-B, PHE1BProtein level used designations for PDHE1-B
- pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- pyruvate dehydrogenase, E1 beta polypeptide
- PDHE1-B
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