PDGFRB Products
(Platelet Derived Growth Factor Receptor beta (PDGFRB))
Categories
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor\; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008].
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Featured PDGFRB Categories
PDGFRB Antibodies
High quality antibodies with extensive validation data.
PDGFRB ELISA Kits
Reliable ELISA kits for a wide range of species.
PDGFRB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PDGFRB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, PLA
Validations
- (6)
Cat. No.
ABIN518746
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (8)
Cat. No.
ABIN3023139
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Validations
- (5)
Cat. No.
ABIN726635
Quantity
100 μL
Datasheet
Datasheet
Recommended PDGFRB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6958652
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958653
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969418
Quantity
96 tests
Datasheet
Datasheet
Recommended PDGFRB Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275445
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275443
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275446
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PDGFRB products
: "Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism." in: Molecular neurodegeneration, Vol. 13, Issue 1, pp. 57, (2019) (PubMed).: "The expression of Platelet-derived Growth factor receptors (PDGFRs) and their correlation with overall survival of patients with ovarian cancer." in: Ginekologia polska, Vol. 90, Issue 5, pp. 242-249, (2019) (PubMed).
: "Phenotypic Characterization of Bone Marrow Mononuclear Cells and Derived Stromal Cell Populations from Human Iliac Crest, Vertebral Body and Femoral Head." in: International journal of molecular sciences, Vol. 20, Issue 14, (2019) (PubMed).
: "Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module." in: Nature neuroscience, Vol. 22, Issue 11, pp. 1892-1902, (2019) (PubMed).
: "Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis." in: Haematologica, (2019) (PubMed).
: "VEGF-A/VEGFR-2 and FGF-2/FGFR-1 but not PDGF-BB/PDGFR-β play important roles in promoting immature and inflammatory intraplaque angiogenesis." in: PLoS ONE, Vol. 13, Issue 8, pp. e0201395, (2018) (PubMed).
: "Platelet-Derived Growth Factor Receptor-Positive Pericytic Cells of White Adipose Tissue from Critical Limb Ischemia Patients Display Mesenchymal Stem Cell-Like Properties." in: Clinics in orthopedic surgery, Vol. 9, Issue 2, pp. 239-248, (2018) (PubMed).
: "Reductions in brain pericytes are associated with arteriovenous malformation vascular instability." in: Journal of neurosurgery, Vol. 129, Issue 6, pp. 1464-1474, (2018) (PubMed).
: "A tissue-specific role for intraflagellar transport genes during craniofacial development." in: PLoS ONE, Vol. 12, Issue 3, pp. e0174206, (2017) (PubMed).
: "Transcriptome analysis of PDGFRα+ cells identifies T-type Ca2+ channel CACNA1G as a new pathological marker for PDGFRα+ cell hyperplasia." in: PLoS ONE, Vol. 12, Issue 8, pp. e0182265, (2017) (PubMed).
Synonyms and alternative names related to PDGFRB
platelet derived growth factor receptor, beta polypeptide (Pdgfrb), platelet derived growth factor receptor beta (Pdgfrb), platelet derived growth factor receptor beta (PDGFRB), AI528809, CD140b, CD140B, IBGC4, JTK12, Pdgfr, PDGFR, PDGFR-1, PDGFR1Protein level used designations for PDGFRB
- CD140 antigen-like family member B
- PDGF beta chain
- PDGF-R-beta
- PDGFR-beta
- beta platelet-derived growth factor receptor
- beta-type platelet-derived growth factor receptor
- platelet-derived growth factor receptor 1
- platelet-derived growth factor receptor beta
- platelet-derived growth factor receptor beta variant 1
- Platelet-derived growth factor receptor, beta
- protein tyrosin kinase
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