PDGFRA Products
(Platelet Derived Growth Factor Receptor alpha (PDGFRA))
Categories
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012].
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Featured PDGFRA Categories
PDGFRA Antibodies
High quality antibodies with extensive validation data.
PDGFRA ELISA Kits
Reliable ELISA kits for a wide range of species.
PDGFRA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PDGFRA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (2)
- (6)
Cat. No.
ABIN5611263
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN392024
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, ICC
Validations
- (5)
Cat. No.
ABIN5542490
Quantity
100 μL
Datasheet
Datasheet
Recommended PDGFRA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
Cat. No.
ABIN6720580
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969416
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969415
Quantity
96 tests
Datasheet
Datasheet
Recommended PDGFRA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275439
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275438
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275440
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PDGFRA products
: "Extracellular Vesicles Derived from Acidified Metastatic Melanoma Cells Stimulate Growth, Migration, and Stemness of Normal Keratinocytes." in: , Vol. 10, Issue 3, (2022) (PubMed).: "SLURP-1 Controls Growth and Migration of Lung Adenocarcinoma Cells, Forming a Complex With α7-nAChR and PDGFR/EGFR Heterodimer." in: Frontiers in cell and developmental biology, Vol. 9, pp. 739391, (2021) (PubMed).
: "A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma." in: Scientific reports, Vol. 9, Issue 1, pp. 4902, (2019) (PubMed).
: "The expression of Platelet-derived Growth factor receptors (PDGFRs) and their correlation with overall survival of patients with ovarian cancer." in: Ginekologia polska, Vol. 90, Issue 5, pp. 242-249, (2019) (PubMed).
: "Clinical genomic sequencing of pediatric and adult osteosarcoma reveals distinct molecular subsets with potentially targetable alterations." in: Clinical cancer research : an official journal of the American Association for Cancer Research, (2019) (PubMed).
: "AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 27, Issue 9, pp. 1568-1585, (2019) (PubMed).
: "An RNA Aptamer Targeting the Receptor Tyrosine Kinase PDGFRα Induces Anti-tumor Effects through STAT3 and p53 in Glioblastoma." in: Molecular therapy. Nucleic acids, Vol. 14, pp. 131-141, (2019) (PubMed).
: "Identification of a multipotent Twist2-expressing cell population in the adult heart." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 36, pp. E8430-E8439, (2018) (PubMed).
: "A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells." in: PLoS pathogens, Vol. 13, Issue 4, pp. e1006273, (2017) (PubMed).
: "Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations." in: Cell stem cell, Vol. 21, Issue 2, pp. 179-194.e4, (2017) (PubMed).
Synonyms and alternative names related to PDGFRA
platelet derived growth factor receptor alpha (PDGFRA), platelet derived growth factor receptor, alpha polypeptide (Pdgfra), platelet derived growth factor receptor alpha (Pdgfra), platelet-derived growth factor receptor, alpha polypeptide L homeolog (pdgfra.L), platelet-derived growth factor receptor, alpha polypeptide (PDGFRA), AI115593, APDGFR, CD140a, CD140A, PDGFACE, PDGFR, Pdgfr-2, PDGFR-2, PDGFR-A, PDGFR2, RHEPDGFRAProtein level used designations for PDGFRA
- platelet-derived growth factor receptor, alpha polypeptide
- alpha-type platelet-derived growth factor receptor-like
- Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha)
- CD140 antigen-like family member A
- PDGF alpha chain
- PDGF-R-alpha
- PDGFR-alpha
- alpha-type platelet-derived growth factor receptor
- platelet-derived growth factor alpha receptor
- platelet-derived growth factor receptor alpha
- alpha platelet-derived growth factor receptor
- CD140a antigen
- PDGFRA/BCR fusion
- platelet-derived growth factor receptor 2
- rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein
- tyrosine kinase PDGFR
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