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PDGFC Products

(Platelet-Derived Growth Factor C (PDGFC))

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The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010].

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Featured PDGFC Categories

PDGFC Antibodies

High quality antibodies with extensive validation data.

PDGFC ELISA Kits

Reliable ELISA kits for a wide range of species.

PDGFC Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PDGFC Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (4)
Cat. No. ABIN7189516
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7435250
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (1)
Cat. No. ABIN714566
Quantity 100 μL
Datasheet Datasheet

Recommended PDGFC ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958645
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6975845
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958646
Quantity 96 tests
Datasheet Datasheet

Recommended PDGFC Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1314504
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314502
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN5509488
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our PDGFC products

Kocael, Vatankulu, Şimşek, Cengiz, Kemik, Kocael, Halaç, Sönmezoğlu, Ulualp: "Comparison of (18)F-fluorodeoxyglucose PET/CT findings with vascular endothelial growth factors and receptors in colorectal cancer." in: Tumour biology, Vol. 37, Issue 3, pp. 3871-7, (2017) (PubMed).

Kitsunai, Makino, Sakagami, Mizumoto, Yanagimachi, Atageldiyeva, Takeda, Fujita, Abiko, Takiyama, Haneda: "High glucose induces platelet-derived growth factor-C via carbohydrate response element-binding protein in glomerular mesangial cells." in: Physiological reports, Vol. 4, Issue 6, (2016) (PubMed).

Skjefstad, Richardsen, Donnem, Andersen, Kiselev, Grindstad, Hald, Al-Shibli, Bremnes, Busund, Al-Saad: "The prognostic role of progesterone receptor expression in non-small cell lung cancer patients: Gender-related impacts and correlation with disease-specific survival." in: Steroids, (2015) (PubMed).

Hurley, Adams, Wang, Jiang, Meo Burt, Du, Xiao: "Accelerated Fracture Healing in Transgenic Mice Overexpressing an Anabolic Isoform of Fibroblast Growth Factor 2." in: Journal of cellular biochemistry, (2015) (PubMed).

Glim, Niessen, Everts, van Egmond, Beelen: "Platelet derived growth factor-CC secreted by M2 macrophages induces alpha-smooth muscle actin expression by dermal and gingival fibroblasts." in: Immunobiology, Vol. 218, Issue 6, pp. 924-9, (2013) (PubMed).

Okada, Honda, Campbell, Sakai, Yamashita, Takebuchi, Hada, Shirasaki, Takabatake, Nakamura, Sunagozaka, Tanaka, Fausto, Kaneko: "Acyclic retinoid targets platelet-derived growth factor signaling in the prevention of hepatic fibrosis and hepatocellular carcinoma development." in: Cancer research, Vol. 72, Issue 17, pp. 4459-71, (2012) (PubMed).

Kilvaer, Valkov, Sorbye, Donnem, Smeland, Bremnes, Busund: "Platelet-Derived Growth Factors in Non-GIST Soft-Tissue Sarcomas Identify a Subgroup of Patients with Wide Resection Margins and Poor Disease-Specific Survival." in: Sarcoma, Vol. 2010, pp. 751304, (2011) (PubMed).

Li, Liu, Bin, Wang, Chen, Xiu, Pei, Lai, Chen, Fan, Xie, Tao, Wu: "Mutant hypoxia inducible factor-1? improves angiogenesis and tissue perfusion in ischemic rabbit skeletal muscle." in: Microvascular research, Vol. 81, Issue 1, pp. 26-33, (2011) (PubMed).

Fang, Yan, Komuves, Yonkovich, Sullivan, Stringer, Galbraith, Lokker, Hwang, Nurden, Phillips, Giese: "PDGF C is a selective alpha platelet-derived growth factor receptor agonist that is highly expressed in platelet alpha granules and vascular smooth muscle." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 24, Issue 4, pp. 787-92, (2004) (PubMed).

Eitner, Ostendorf, Kretzler, Cohen, Eriksson, Gröne, Floege: "PDGF-C expression in the developing and normal adult human kidney and in glomerular diseases." in: Journal of the American Society of Nephrology : JASN, Vol. 14, Issue 5, pp. 1145-53, (2003) (PubMed).

Synonyms and alternative names related to PDGFC

platelet derived growth factor C (PDGFC), platelet derived growth factor C (Pdgfc), platelet-derived growth factor, C polypeptide (Pdgfc), 1110064L01Rik, AI647969, FALLOTEIN, PDGF-C, SCDGF

Protein level used designations for PDGFC

  • platelet-derived growth factor C
  • PDGF-C
  • VEGF-E
  • fallotein
  • platelet-derived growth factor, C polypeptide
  • rScdfg
  • spinal cord-derived growth factor
  • secretory growth factor-like protein
  • SCDGF
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