PDGFB Products
(Platelet Derived Growth Factor Subunit B (PDGFB))
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The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2013].
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Featured PDGFB Categories
PDGFB Antibodies
High quality antibodies with extensive validation data.
PDGFB ELISA Kits
Reliable ELISA kits for a wide range of species.
PDGFB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PDGFB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN7223038
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN3021689
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (4)
- (3)
Cat. No.
ABIN725990
Quantity
100 μL
Datasheet
Datasheet
Recommended PDGFB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958642
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958644
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969404
Quantity
96 tests
Datasheet
Datasheet
Recommended PDGFB Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN5509325
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314500
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124479
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our PDGFB products
: "Melatonin promotes osteoblastic differentiation and regulates PDGF/AKT signaling pathway." in: Cell biology international, Vol. 44, Issue 2, pp. 402-411, (2020) (PubMed).: "PDGF-BB homodimer serum level - a good indicator of the severity of alcoholic liver cirrhosis." in: Annals of agricultural and environmental medicine : AAEM, Vol. 27, Issue 1, pp. 80-85, (2020) (PubMed).
: "The Design, Characterizations, and Tumor Angiogenesis Inhibition of a Multi-Epitope Peptibody With bFGF/VEGFA." in: Frontiers in oncology, Vol. 10, pp. 1190, (2020) (PubMed).
: "Immunohistochemical biomarkers and distribution of telocytes in ApoE-/- mice." in: Cell biology international, Vol. 43, Issue 11, pp. 1286-1295, (2020) (PubMed).
: "Leukocyte depletion does not affect the in vitro healing ability of platelet rich plasma." in: Experimental and therapeutic medicine, Vol. 15, Issue 4, pp. 4029-4038, (2018) (PubMed).
: "Discovery of Human-Similar Gene Fusions in Canine Cancers. ..." in: Cancer research, Vol. 77, Issue 21, pp. 5721-5727, (2017) (PubMed).
: "Expression and purification of functional PDGF receptor beta." in: Biochemical and biophysical research communications, Vol. 489, Issue 3, pp. 353-359, (2017) (PubMed).
: "Inhibition of Glomerular Mesangial Cell Proliferation by siPDGF-B- and siPDGFR-β-Containing Chitosan Nanoplexes." in: AAPS PharmSciTech, Vol. 18, Issue 4, pp. 1031-1042, (2016) (PubMed).
: "Vascular endothelial growth factor-dependent angiogenesis and dynamic vascular plasticity in the sensory circumventricular organs of adult mouse brain." in: Cell and tissue research, (2015) (PubMed).
: "Therapeutic efficacy of autologous platelet-rich plasma and polydeoxyribonucleotide on female pattern hair loss." in: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, (2015) (PubMed).
Synonyms and alternative names related to PDGFB
platelet derived growth factor subunit B (PDGFB), platelet-derived growth factor beta polypeptide (PDGFB), platelet derived growth factor subunit B S homeolog (pdgfb.S), platelet-derived growth factor beta polypeptide a (pdgfba), platelet derived growth factor, B polypeptide (Pdgfb), platelet derived growth factor subunit B (Pdgfb), c-sis, PDGF-2, PDGF-B, PDGF2, pdgf2, si:ch211-79m20.1, si:dkey-261d11.1, SIS, sis, Sis, SSVProtein level used designations for PDGFB
- PDGF subunit B
- PDGF, B chain
- becaplermin
- platelet-derived growth factor 2
- platelet-derived growth factor B chain
- platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
- platelet-derived growth factor subunit B
- platelet-derived growth factor, beta polypeptide (oncogene SIS)
- proto-oncogene c-Sis
- platelet-derived growth factor B
- v-sis platelet-derived growth factor beta polypeptide (simian sarcoma viral oncogene homolog)
- PDGF-2
- c-sis
- platelet-derived growth factor beta polypeptide
- Platelet-derived growth factor, same as Sis (Simian sarcoma viral oncogene homologue, c-sis)
- pdgf protein
- platelet derived growth factor, B polypeptide
- platelet-derived growth factor B subunit
- Platelet-derived growth factor B chain
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