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PDGFA Products

(Platelet Derived Growth Factor A (PDGFA))

Categories

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis\; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008].

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Featured PDGFA Categories

PDGFA Antibodies

High quality antibodies with extensive validation data.

PDGFA ELISA Kits

Reliable ELISA kits for a wide range of species.

PDGFA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PDGFA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
  • (3)
Cat. No. ABIN726155
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, PLA
Validations
  • (3)
Cat. No. ABIN518737
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN388459
Quantity 400 μL
Datasheet Datasheet

Recommended PDGFA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958637
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958638
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6973871
Quantity 96 tests
Datasheet Datasheet

Recommended PDGFA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN5509326
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1314496
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (3)
Cat. No. ABIN6239819
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our PDGFA products

Wang, Zhou, Li, Shang: "Shikonin alleviates allergic airway remodeling by inhibiting the ERK-NF-κB signaling pathway." in: International immunopharmacology, Vol. 48, pp. 169-179, (2018) (PubMed).

Sayin, Micili, Goker, Kamaci, Ergur, Yilmaz, Guner Akdogan: "The role of resveratrol on full - Thickness uterine wound healing in rats." in: Taiwanese journal of obstetrics & gynecology, Vol. 56, Issue 5, pp. 657-663, (2018) (PubMed).

Dik, Baş, Yazıhan: "The effect of midkine on growth factors and oxidative status in an experimental wound model in diabetic and healthy rats." in: Canadian journal of physiology and pharmacology, Vol. 95, Issue 5, pp. 604-609, (2017) (PubMed).

Eren, Turgut, Akin, Demir: "The Suppression of Wound Healing Response with Sirolimus and Sunitinib Following Experimental Trabeculectomy in a Rabbit Model." in: Current eye research, Vol. 41, Issue 3, pp. 367-76, (2016) (PubMed).

Lee, Zheng, Kang, Kim, Oh, Cho: "Therapeutic efficacy of autologous platelet-rich plasma and polydeoxyribonucleotide on female pattern hair loss." in: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, (2015) (PubMed).

Paule, Nebl, Webb, Vollenhoven, Rombauts, Nie: "Proprotein convertase 5/6 cleaves platelet-derived growth factor A in the human endometrium in preparation for embryo implantation." in: Molecular human reproduction, Vol. 21, Issue 3, pp. 262-70, (2015) (PubMed).

Tang, Chen, Chiang, Chen, Chang, Chen: "Differentiation Effects of Platelet-Rich Plasma Concentrations on Synovial Fluid Mesenchymal Stem Cells from Pigs Cultivated in Alginate Complex Hydrogel." in: International journal of molecular sciences, Vol. 16, Issue 8, pp. 18507-21, (2015) (PubMed).

Yu, Zhou, Xue, Huang, Zhang, Kang, Chiu, Tan, Xie, Wang, Huang: "FoxM1 promotes breast tumorigenesis by activating PDGF-A and forming a positive feedback loop with the PDGF/AKT signaling pathway." in: Oncotarget, Vol. 6, Issue 13, pp. 11281-94, (2015) (PubMed).

Koca Kutlu, Ceçen, Gürgen, Say?n, Cetin: "A Comparison Study of Growth Factor Expression following Treatment with Transcutaneous Electrical Nerve Stimulation, Saline Solution, Povidone-Iodine, and Lavender Oil in Wounds Healing." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2013, pp. 361832, (2013) (PubMed).

Wehler, Hamdi, Maderer, Graf, Gockel, Schmidtmann, Hainz, Berger, Theobald, Galle, Moehler, Schimanski: "Single-agent therapy with sorafenib or 5-FU is equally effective in human colorectal cancer xenograft--no benefit of combination therapy." in: International journal of colorectal disease, Vol. 28, Issue 3, pp. 385-98, (2013) (PubMed).

Synonyms and alternative names related to PDGFA

platelet derived growth factor subunit A (PDGFA), platelet-derived growth factor alpha polypeptide a (pdgfaa), platelet derived growth factor subunit A (pdgfa), coagulation factor III (F3), platelet derived growth factor, alpha (Pdgfa), platelet derived growth factor subunit A (Pdgfa), platelet derived growth factor subunit A S homeolog (pdgfa.S), platelet-derived growth factor alpha polypeptide b (pdgfab), AA409063, CD142, Cf-3, Cf3, pdgf, PDGF-A, pdgf-a, PDGF1, pdgf1, pdgfa, pdgfa-2, PDGFACP, TF, wu:fc32c12, zgc:100777, zgc:153249

Protein level used designations for PDGFA

  • PDGF A-chain
  • PDGF subunit A
  • PDGF-1
  • platelet-derived growth factor A chain
  • platelet-derived growth factor alpha chain
  • platelet-derived growth factor alpha isoform 2 preproprotein
  • platelet-derived growth factor subunit A
  • platelet-derived growth factor alpha polypeptide
  • tissue factor
  • Platelet-derived growth factor A chain
  • platelet derived growth factor, alpha
  • PDGF-A (S1)
  • platelet-derived growth factor A chain long form
  • platelet-derived growth factor A chain short form type 1
  • platelet-derived growth factor A chain short form type 2
  • platelet-derived growth factor A-chain
  • platelet-derived growth factor A chain, long form
  • platelet derived growth factor alpha b
  • platelet-derived growth factor alpha polypeptide b
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