PDE6B Products
(phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
Categories
Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009].
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Featured PDE6B Categories
PDE6B Antibodies
High quality antibodies with extensive validation data.
PDE6B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PDE6B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN6145363
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (2)
Cat. No.
ABIN7262851
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6748130
Quantity
100 μL
Datasheet
Datasheet
Recommended PDE6B ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6231751
Quantity
96 tests
Datasheet
Datasheet
Recommended PDE6B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Human, Mouse, Pig, Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2750996
Quantity
5 applications
Datasheet
Datasheet
Latest Publications for our PDE6B products
: "Expression of phosphodiesterase 6 (PDE6) in human breast cancer cells." in: SpringerPlus, Vol. 2, pp. 680, (2014) (PubMed).: "Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis." in: Respiratory research, Vol. 11, pp. 146, (2011) (PubMed).
Synonyms and alternative names related to PDE6B
phosphodiesterase 6B (PDE6B), phosphodiesterase 6B (Pde6b), phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide (Pde6b), CSNB3, CSNBAD2, PDBS, PDEB, Pdeb, r, RCD-1, rd, rd-1, rd1, rd10, RP40Protein level used designations for PDE6B
- GMP-PDE beta
- rod cGMP-phosphodiesterase beta-subunit
- rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
- pde6B gene for cGMP phosphodiesterase beta subunit
- phosphodiesterase 6B, cGMP-specific, rod, beta (congenital stationary night blindness 3, autosomal dominant)
- rod cGMP phosphodiesterase beta subunit
- phosphodiesterase, cyclic GMP ( rod receptor), beta polypeptide
- phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide
- cGMP-phosphodiesterase beta-subunit
- phosphodiesterase, cGMP, rod receptor, beta polypeptide
- retinal degeneration 1
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