PDE5A Products
(phosphodiesterase 5A, cGMP-Specific (PDE5A))
Categories
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
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Featured PDE5A Categories
PDE5A Antibodies
High quality antibodies with extensive validation data.
PDE5A ELISA Kits
Reliable ELISA kits for a wide range of species.
PDE5A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PDE5A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, FACS
Validations
- (4)
Cat. No.
ABIN185350
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (3)
Cat. No.
ABIN563735
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (1)
- (2)
Cat. No.
ABIN2789423
Quantity
100 μL
Datasheet
Datasheet
Recommended PDE5A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969266
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969265
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958535
Quantity
96 tests
Datasheet
Datasheet
Recommended PDE5A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314473
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7414600
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136441
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PDE5A products
: "Novel effect of sildenafil on hair growth." in: Biochemical and biophysical research communications, Vol. 505, Issue 3, pp. 685-691, (2018) (PubMed).: "PDE5 Exists in Human Neurons and is a Viable Therapeutic Target for Neurologic Disease." in: Journal of Alzheimer's disease : JAD, Vol. 52, Issue 1, pp. 295-302, (2016) (PubMed).
: "Expression and Function of Phosphodiesterase Type 5 in Human Breast Cancer Cell Lines and Tissues: Implications for Targeted Therapy." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 9, pp. 2271-82, (2016) (PubMed).
: "A phosphodiesterase type-5 inhibitor, sildenafil, induces sperm capacitation and penetration into porcine oocytes in a chemically defined medium." in: Theriogenology, Vol. 85, Issue 3, pp. 428-33, (2016) (PubMed).
: "Role of Ser102 and Ser104 as regulators of cGMP hydrolysis by PDE5A." in: PLoS ONE, Vol. 9, Issue 9, pp. e107627, (2015) (PubMed).
: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." in: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, (2015) (PubMed).
: "Expression and distribution of phosphodiesterase isoenzymes in the human male urethra." in: Urology, Vol. 85, Issue 4, pp. 964.e1-6, (2015) (PubMed).
: "Phosphodiesterase 1 regulation is a key mechanism in vascular aging." in: Clinical science (London, England : 1979), Vol. 129, Issue 12, pp. 1061-75, (2015) (PubMed).
: "Effect of sildenafil on skeletal and cardiac muscle in Becker muscular dystrophy." in: Annals of neurology, Vol. 76, Issue 4, pp. 550-7, (2014) (PubMed).
: "Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5)." in: International journal of impotence research, Vol. 23, Issue 5, pp. 206-12, (2012) (PubMed).
Synonyms and alternative names related to PDE5A
phosphodiesterase 5A (PDE5A), phosphodiesterase 5A (Pde5a), phosphodiesterase 5A, cGMP-specific (Pde5a), phosphodiesterase 5A S homeolog (pde5a.S), phosphodiesterase 5A, cGMP-specific, b (pde5ab), phosphodiesterase 5A (pde5a), CGB-PDE, cgb-pde, Cgbpde, CN5A, cn5a, Cn5n, PDE5, Pde5, pde5, PDE5A, pde5a, Pde5a1, pde5a1, PDE5A2Protein level used designations for PDE5A
- cGMP-binding cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase
- cGMP-specific 3',5'-cyclic phosphodiesterase
- cGMP-specific phosphodiesterase PDE5A2
- cGMP-specific phosphodiesterase type 5A
- phosphodiesterase isozyme 5
- CGB-PDE
- cGMP-binding cGMP specific phosphodiesterase 5A2
- cGMP-binding cGMP-specific phosphodiesterase
- phosphodiesterase type 5
- cGMP-binding/cGMP-specific phosphodiesterase
- 3',5'-Cyclic GMP Phosphodiesterase
- phosphodiesterase 5A, cGMP-specific
- phosphodiesterase 5a, cGMP-specific
- phosphodiesterase 5a
- cGMP-specific 3',5'-cyclic phosphodiesterase-like
- cyclic nucleotide phosphodiesterase 5a
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