PDE1A Products
(Phosphodiesterase 1A (PDE1A))
Categories
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1\; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]\; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009].
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Featured PDE1A Categories
PDE1A Antibodies
High quality antibodies with extensive validation data.
PDE1A ELISA Kits
Reliable ELISA kits for a wide range of species.
PDE1A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PDE1A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7441283
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Mouse, Rat
Application
WB
Validations
- (4)
Cat. No.
ABIN2785487
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6264086
Quantity
100 μL
Datasheet
Datasheet
Recommended PDE1A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958529
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5657765
Quantity
96 tests
Datasheet
Datasheet
Recommended PDE1A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314449
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314451
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408210
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PDE1A products
: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." in: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, (2015) (PubMed).: "Expression and distribution of phosphodiesterase isoenzymes in the human male urethra." in: Urology, Vol. 85, Issue 4, pp. 964.e1-6, (2015) (PubMed).
: "Phosphodiesterase type 1, calcitonin gene-related peptide and vasoactive intestinal polypeptide are involved in the control of human vaginal arterial vessels." in: European journal of obstetrics, gynecology, and reproductive biology, Vol. 169, Issue 2, pp. 283-6, (2014) (PubMed).
: "Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling." in: Biochimica et biophysica acta, Vol. 1842, Issue 7, pp. 916-26, (2014) (PubMed).
: "Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1." in: Molecular nutrition & food research, Vol. 55, Issue 11, pp. 1677-89, (2012) (PubMed).
: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).
: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).
: "Association study of phosphodiesterase genes in the Sequenced Treatment Alternatives to Relieve Depression sample." in: Pharmacogenetics and genomics, Vol. 19, Issue 3, pp. 235-8, (2009) (PubMed).
: "Calcium-dependent phosphodiesterase 1C inhibits renin release from isolated juxtaglomerular cells." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 297, Issue 5, pp. R1469-76, (2009) (PubMed).
: "Gene expression and protein localization of calmodulin-dependent phosphodiesterase during ontogenesis of chick retina." in: Journal of neuroscience research, Vol. 86, Issue 5, pp. 1017-23, (2008) (PubMed).
Synonyms and alternative names related to PDE1A
phosphodiesterase 1A (PDE1A), phosphodiesterase 1A, calmodulin-dependent (pde1a), phosphodiesterase 1A (pde1a), phosphodiesterase 1A, calmodulin-dependent (PDE1A), phosphodiesterase 1A (Pde1a), phosphodiesterase 1A, calmodulin-dependent (Pde1a), 3'-RACEclone8phosphodiesterase1A, 3-RACEclone8phosphodiesterase1A, AI987702, AW125737, CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A, PDE1, PDE1AProtein level used designations for PDE1A
- calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
- calmodulin-activated cyclic nucleotide phosphodiesterase
- phosphodiesterase 1A, calmodulin-dependent
- calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like
- cyclic nucleotide phosphodiesterase 1a
- 61 kDa Cam-PDE
- calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase
- cam-PDE 1A
- 3'-RACE clone 8 phosphodiesterase 1A
- 3-RACE clone 8 phosphodiesterase 1A
- calmodulin-dependent phosphodiesterase type 1
- nucleotide phosphodiesterase, 3'-5'-cyclic
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