PDE11A Products
(phosphodiesterase 11A (PDE11A))
Categories
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured PDE11A Categories
PDE11A Antibodies
High quality antibodies with extensive validation data.
PDE11A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PDE11A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7150681
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC
Validations
- (2)
Cat. No.
ABIN195735
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN213553
Quantity
50 μg
Datasheet
Datasheet
Recommended PDE11A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094408
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3132723
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2728475
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our PDE11A products
: "Does phosphodiesterase 11A (PDE11A) hold promise as a future therapeutic target?" in: Current pharmaceutical design, Vol. 21, Issue 3, pp. 389-416, (2015) (PubMed).: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).
: "Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain." in: Cellular signalling, Vol. 26, Issue 2, pp. 383-97, (2014) (PubMed).
: "Potential therapeutic applications of phosphodiesterase inhibition in prostate cancer." in: World journal of urology, Vol. 31, Issue 2, pp. 325-30, (2013) (PubMed).
: "Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5)." in: International journal of impotence research, Vol. 23, Issue 5, pp. 206-12, (2012) (PubMed).
: "Expression and distribution of phosphodiesterase isoenzymes in the human seminal vesicles." in: The journal of sexual medicine, Vol. 8, Issue 11, pp. 3058-65, (2012) (PubMed).
: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).
: "Analysis of genetic variants of phosphodiesterase 11A in acromegalic patients." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 161, Issue 5, pp. 687-94, (2009) (PubMed).
: "PDE9A, PDE10A, and PDE11A expression in rat trigeminovascular pain signalling system." in: Brain research, Vol. 1281, pp. 25-34, (2009) (PubMed).
: "Immunohistochemical distribution of cAMP- and cGMP-phosphodiesterase (PDE) isoenzymes in the human prostate." in: European urology, Vol. 49, Issue 4, pp. 740-5, (2007) (PubMed).
Synonyms and alternative names related to PDE11A
phosphodiesterase 11A (PDE11A), phosphodiesterase 11A (Pde11a), phosphodiesterase 11a (pde11a), phosphodiesterase 11A (pde11a), dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (LOC100470038), dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Pde11a), 6330414F14Rik, A630086N24Rik, Gm350, PDE11A, Pde11a, PDE11A1, PPNAD2, ppnad2, si:ch211-222f23.5Protein level used designations for PDE11A
- cAMP and cGMP cyclic nucleotide phosphodiesterase 11A
- dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
- cAMP and cGMP phosphodiesterase 11A
- phosphodiesterase 11A
- dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like
- phosphodiesterase 11a
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