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PDCD6 Products

(Programmed Cell Death 6 (PDCD6))
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012].

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Featured PDCD6 Categories

PDCD6 Antibodies

High quality antibodies with extensive validation data.

PDCD6 ELISA Kits

Reliable ELISA kits for a wide range of species.

PDCD6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PDCD6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7430027
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN2866332
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7164696
Quantity 100 μg
Datasheet Datasheet

Recommended PDCD6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958804
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5690931
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384929
Quantity 96 tests
Datasheet Datasheet

Recommended PDCD6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124577
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314428
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314430
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PDCD6 products

Vergarajauregui, Martina, Puertollano: "Identification of the penta-EF-hand protein ALG-2 as a Ca2+-dependent interactor of mucolipin-1." in: The Journal of biological chemistry, Vol. 284, Issue 52, pp. 36357-66, (2009) (PubMed).

Okumura, Ichioka, Kobayashi, Suzuki, Yoshida, Shibata, Maki: "Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101." in: Biochemical and biophysical research communications, Vol. 386, Issue 1, pp. 237-41, (2009) (PubMed).

Abe, Miyakushi, Nagai, Norimatsu: "Study of the factors affecting the photoelectrode characteristics of a perylene/phthalocyanine bilayer working in the water phase." in: Physical chemistry chemical physics : PCCP, Vol. 10, Issue 11, pp. 1562-8, (2008) (PubMed).

Yamada, Arao, Gotoda, Taniguchi, Oda, Shirao, Shimada, Hamaguchi, Kato, Hamano, Koizumi, Tamura, Saito, Shimoda, Saka, Fukagawa, Katai, Sano, Sasako, Nishio: "Identification of prognostic biomarkers in gastric cancer using endoscopic biopsy samples." in: Cancer science, Vol. 99, Issue 11, pp. 2193-9, (2008) (PubMed).

Kitaura, Satoh, Takahashi, Shibata, Maki: "Both ALG-2 and peflin, penta-EF-hand (PEF) proteins, are stabilized by dimerization through their fifth EF-hand regions." in: Archives of biochemistry and biophysics, Vol. 399, Issue 1, pp. 12-8, (2002) (PubMed).

Kitaura, Matsumoto, Satoh, Hitomi, Maki: "Peflin and ALG-2, members of the penta-EF-hand protein family, form a heterodimer that dissociates in a Ca2+-dependent manner." in: The Journal of biological chemistry, Vol. 276, Issue 17, pp. 14053-8, (2001) (PubMed).

Synonyms and alternative names related to PDCD6

programmed cell death 6 L homeolog (pdcd6.L), programmed cell death 6 (pdcd6), programmed cell death 6 (PDCD6), programmed cell death 6 (Pdcd6), ALG-2, alg-2, Alg2, AV299538, MA-3, MGC52821, MGC132114, pdcd6, PDCD6, PEF1B, PS2, zgc:63952

Protein level used designations for PDCD6

  • programmed cell death 6
  • programmed cell death protein 6
  • apoptosis-linked gene 2 protein
  • probable calcium-binding protein ALG-2
  • ALG-257
  • PMP41
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