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PCSK9 Proteins

(Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq, Jul 2008].

recommended

PCSK9 Protein (AA 31-692) (His tag) (ABIN7275415)

PCSK9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

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recommended

PCSK9 Protein (AA 35-694) (His tag) (ABIN7275416)

PCSK9 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

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recommended

PCSK9 Protein (AA 31-692) (His tag) (ABIN2181580)

PCSK9 Origin: Human Host: HEK-293 Cells Recombinant >97 % as determined by SDS-PAGE. Active

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PCSK9 Proteins by Origin

Find PCSK9 Proteins for a variety of species such as anti-Human PCSK9, anti-Mouse PCSK9, anti-Rat PCSK9. The species listed below are among those available. Click on a link to go to the corresponding products.

PCSK9 Proteins by Source

Here you will find PCSK9 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

PCSK9 Proteins by Protein Type

Here you can find PCSK9 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

PCSK9 Proteins by Application

Find PCSK9 Proteins validated for a specific application such as WB, PC, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PCSK9 Proteins by Biological Activity

Find PCSK9 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular PCSK9 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

PCSK9 Protein (AA 31-692) (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7275415

Quantity 100 μg

Datasheet Datasheet

PCSK9 Protein (AA 35-694) (His tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7275416

Quantity 100 μg

Datasheet Datasheet

PCSK9 Protein (AA 31-692) (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

(10)
(3)

Cat. No. ABIN2181580

Quantity 50 μg

Datasheet Datasheet

PCSK9 Protein (AA 151-811) (His tag)

Reactivity Cynomolgus

Source HEK-293 Cells

Validations

Cat. No. ABIN7275414

Quantity 100 μg

Datasheet Datasheet

PCSK9 Protein (AA 31-692) (His tag,AVI tag,Biotin)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2444171

Quantity 200 μg

Datasheet Datasheet

PCSK9 Protein (AA 31-692) (Fc Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN6388267

Quantity 50 μg

Datasheet Datasheet

PCSK9 Protein (AA 31-692) (Fc Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7092725

Quantity 100 μg

Datasheet Datasheet

PCSK9 Protein (AA 1-678) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN3013383

Quantity 10 μg

Datasheet Datasheet

PCSK9 Protein (His tag)

Reactivity Rat

Source HEK-293 Cells

Validations

Cat. No. ABIN7321244

Quantity 20 μg

Datasheet Datasheet

PCSK9 Protein (His tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7320347

Quantity 100 μg

Datasheet Datasheet

PCSK9 Protein (AA 31-691) (His tag)

Reactivity Rat

Source HEK-293 Cells

Validations

Cat. No. ABIN2181592

Quantity 50 μg

Datasheet Datasheet

PCSK9 Protein (AA 31-692) (His tag)

Reactivity Cynomolgus

Source HEK-293 Cells

Validations

Cat. No. ABIN2870599

Quantity 50 μg

Datasheet Datasheet

PCSK9 Protein (AA 30-691) (His tag)

Reactivity Hamster

Source HEK-293 Cells

Validations

Cat. No. ABIN2870601

Quantity 50 μg

Datasheet Datasheet

PCSK9 Protein (AA 35-694) (His tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN2181589

Quantity 100 μg

Datasheet Datasheet

PCSK9 Protein (AA 35-694) (His tag,AVI tag,Biotin)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN2870574

Quantity 200 μg

Datasheet Datasheet

Latest Publications for our PCSK9 Proteins

Wang, Amiss, Weidmann, Craik: "Structure-activity analysis of truncated albumin-binding domains suggests new lead constructs for potential therapeutic delivery." in: The Journal of biological chemistry, Vol. 295, Issue 34, pp. 12143-12152, (2021) (PubMed).

Burnap, Sattler, Pechlaner, Duregotti, Lu, Theofilatos, Takov, Heusch, Tsimikas, Fernandez-Hernando, Berry, Hall, Notdurfter, Rungger, Paulweber, Willeit, Kiechl, Levkau, Mayr: "PCSK9 Activity Is Potentiated Through HDL Binding." in: Circulation research, (2021) (PubMed).

Chen, Lichtor, Berliner, Chen, Liu: "Evolution of sequence-defined highly functionalized nucleic acid polymers." in: Nature chemistry, Vol. 10, Issue 4, pp. 420-427, (2019) (PubMed).

Lichtor, Chen, Elowe, Chen, Liu: "Side chain determinants of biopolymer function during selection and replication." in: Nature chemical biology, Vol. 15, Issue 4, pp. 419-426, (2019) (PubMed).

Wijers, Zanoni, Liv, Vos, Jäckstein, Smit, Wilbrink, Wolters, van der Veen, Huijkman, Dekker, Kloosterhuis, van Dijk, Billadeau, Kuipers, Klumperman, von Eckardstein, Kuivenhoven, van de Sluis: "The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance." in: JCI insight, Vol. 4, Issue 11, (2019) (PubMed).

Wang, Ghani, Bundock, Weidmann, Harvey, Edwards, Schroeder, Swedberg, Craik: "Calcium-Mediated Allostery of the EGF Fold." in: ACS chemical biology, Vol. 13, Issue 6, pp. 1659-1667, (2019) (PubMed).

Grin, Dwivedi, Chathely, Trigatti, Prat, Seidah, Liaw, Fox-Robichaud: "Low-density lipoprotein (LDL)-dependent uptake of Gram-positive lipoteichoic acid and Gram-negative lipopolysaccharide occurs through LDL receptor." in: Scientific reports, Vol. 8, Issue 1, pp. 10496, (2018) (PubMed).

Dugardin, Briand, Touche, Schonewille, Moreau, Le May, Groen, Staels, Lestavel: "Retrograde cholesterol transport in the human Caco-2/TC7 cell line: a model to study trans-intestinal cholesterol excretion in atherogenic and diabetic dyslipidemia." in: Acta diabetologica, Vol. 54, Issue 2, pp. 191-199, (2017) (PubMed).

Susan-Resiga, Girard, Kiss, Essalmani, Hamelin, Asselin, Awan, Butkinaree, Fleury, Soldera, Dory, Baass, Seidah: "The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation: A NOVEL MECHANISM CAUSING FAMILIAL HYPERCHOLESTEROLEMIA." in: The Journal of biological chemistry, Vol. 292, Issue 5, pp. 1573-1590, (2017) (PubMed).

Topchiy, Cirstea, Kong, Boyd, Wang, Russell, Walley: "Lipopolysaccharide Is Cleared from the Circulation by Hepatocytes via the Low Density Lipoprotein Receptor." in: PLoS ONE, Vol. 11, Issue 5, pp. e0155030, (2017) (PubMed).

Aliases for PCSK9 Proteins

proprotein convertase subtilisin/kexin type 9 (PCSK9) Proteins
proprotein convertase subtilisin/kexin type 9 L homeolog (pcsk9.L) Proteins
proprotein convertase subtilisin/kexin type 9 (pcsk9) Proteins
proprotein convertase subtilisin/kexin type 9 (Pcsk9) Proteins
AI415265 Proteins
AI747682 Proteins
FH3 Proteins
HCHOLA3 Proteins
LDLCQ1 Proteins
NARC-1 Proteins
NARC1 Proteins
Narc1 Proteins
PC9 Proteins

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PCSK9 Proteins by Origin

PCSK9 Proteins by Source

PCSK9 Proteins by Protein Type

PCSK9 Proteins by Application

PCSK9 Proteins by Biological Activity

Popular PCSK9 Proteins

Latest Publications for our PCSK9 Proteins

Aliases for PCSK9 Proteins

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