PCSK9 Products
(Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
Categories
This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq, Jul 2008].
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Featured PCSK9 Categories
PCSK9 Antibodies
High quality antibodies with extensive validation data.
PCSK9 ELISA Kits
Reliable ELISA kits for a wide range of species.
PCSK9 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PCSK9 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (7)
Cat. No.
ABIN652320
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (6)
Cat. No.
ABIN6145328
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7427117
Quantity
100 μL
Datasheet
Datasheet
Recommended PCSK9 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6962331
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6963307
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6973907
Quantity
96 tests
Datasheet
Datasheet
Recommended PCSK9 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7275415
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275416
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (10)
- (3)
Cat. No.
ABIN2181580
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our PCSK9 products
: "Structure-activity analysis of truncated albumin-binding domains suggests new lead constructs for potential therapeutic delivery." in: The Journal of biological chemistry, Vol. 295, Issue 34, pp. 12143-12152, (2021) (PubMed).: "PCSK9 Activity Is Potentiated Through HDL Binding." in: Circulation research, (2021) (PubMed).
: "Effect of Sleeve Gastrectomy on Proprotein Convertase Subtilisin/Kexin Type 9 (Pcsk9) Content and Lipid Metabolism in the Blood Plasma and Liver of Obese Wistar Rats." in: Nutrients, Vol. 11, Issue 9, (2020) (PubMed).
: "The relationship between protein convertase subtilisin kexin type-9 levels and extent of coronary artery disease in patients with non-ST-elevation myocardial infarction." in: Coronary artery disease, Vol. 31, Issue 1, pp. 81-86, (2020) (PubMed).
: "Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained." in: The Journal of biological chemistry, Vol. 293, Issue 19, pp. 7329-7343, (2019) (PubMed).
: "New Insight on a Combination of Policosanol and 10-Dehydrogingerdione Phytochemicals as Inhibitors for Platelet Activation Biomarkers and Atherogenicity Risk in Dyslipidemic Rabbits: Role of CETP and ..." in: Applied biochemistry and biotechnology, Vol. 186, Issue 4, pp. 805-815, (2019) (PubMed).
: "Dyslipidemia induced inflammatory status, platelet activation and endothelial dysfunction in rabbits: Protective role of 10-Dehydrogingerdione." in: Biomedicine & pharmacotherapy, Vol. 110, pp. 456-464, (2019) (PubMed).
: "Evolution of sequence-defined highly functionalized nucleic acid polymers." in: Nature chemistry, Vol. 10, Issue 4, pp. 420-427, (2019) (PubMed).
: "Side chain determinants of biopolymer function during selection and replication." in: Nature chemical biology, Vol. 15, Issue 4, pp. 419-426, (2019) (PubMed).
: "The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance." in: JCI insight, Vol. 4, Issue 11, (2019) (PubMed).
Synonyms and alternative names related to PCSK9
proprotein convertase subtilisin/kexin type 9 (PCSK9), proprotein convertase subtilisin/kexin type 9 L homeolog (pcsk9.L), proprotein convertase subtilisin/kexin type 9 (pcsk9), proprotein convertase subtilisin/kexin type 9 (Pcsk9), AI415265, AI747682, FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, Narc1, PC9Protein level used designations for PCSK9
- convertase subtilisin/kexin type 9 preproprotein
- neural apoptosis regulated convertase 1
- subtilisin/kexin-like protease PC9
- proprotein convertase 9
- proprotein convertase PC9
- proprotein convertase subtilisin/kexin type 9
- proprotein convertase subtilisin/kexin type 9 preproprotein
- NARC-1
- convertase subtilisin
- neural apoptosis-regulated convertase 1
- Proprotein convertase 9
- Subtilisin/kexin-like protease PC9
- LOW QUALITY PROTEIN: proprotein convertase subtilisin/kexin type 9
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