PCSK6 Products
(Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))
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The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Featured PCSK6 Categories
PCSK6 Antibodies
High quality antibodies with extensive validation data.
Recommended PCSK6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
- (5)
Cat. No.
ABIN562089
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
- (3)
Cat. No.
ABIN308447
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Horse, Human, Monkey, Rabbit, Rat
Application
ELISA, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN461695
Quantity
50 μg
Datasheet
Datasheet
Recommended PCSK6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958854
Quantity
96 tests
Datasheet
Datasheet
Recommended PCSK6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314361
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PCSK6 products
: "Transcriptome profiling of subepithelial PDGFRα cells in colonic mucosa reveals several cell-selective markers." in: PloS one, Vol. 17, Issue 5, pp. e0261743, (2022) (PubMed).: "Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 33, Issue 10, pp. 2432-43, (2013) (PubMed).
: "Hepatic proprotein convertases modulate HDL metabolism." in: Cell metabolism, Vol. 6, Issue 2, pp. 129-36, (2007) (PubMed).
: "Bioinformatics methods for prioritizing serum biomarker candidates." in: Clinical chemistry, Vol. 52, Issue 11, pp. 2162-4, (2007) (PubMed).
: "Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy." in: The American journal of pathology, Vol. 160, Issue 6, pp. 1921-35, (2002) (PubMed).
Synonyms and alternative names related to PCSK6
proprotein convertase subtilisin/kexin type 6 (PCSK6), peptidase S8 (EAMY_RS27925), proprotein convertase subtilisin/kexin type 6 (pcsk6), proprotein convertase subtilisin/kexin type 6 (Pcsk6), proprotein convertase subtilisin/kexin type 6 L homeolog (pcsk6.L), C86343, PACE4, Pace4, PACE4AIIa, PCSK6, SPC4, Spc4, spc4, Xpace4Protein level used designations for PCSK6
- proprotein convertase PACE4
- proprotein convertase subtilisin/kexin type 6
- proprotein convertase subtilisin/kexin type 6-like
- paired basic amino acid cleaving enzyme 4
- paired basic amino acid cleaving system 4
- subtilisin-like proprotein convertase 4
- subtilisin/kexin-like protease PACE4
- Subtilisin - like endoprotease
- kexin-like protease PC7A
- subtilisin-like kinase SPC4
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