PCNT Products
(Pericentrin (PCNT))
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The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. [provided by RefSeq, Jul 2008].
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Featured PCNT Categories
PCNT Antibodies
High quality antibodies with extensive validation data.
PCNT ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended PCNT Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (3)
Cat. No.
ABIN7444175
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7162877
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN7269216
Quantity
100 μL
Datasheet
Datasheet
Recommended PCNT ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958464
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5657696
Quantity
96 tests
Datasheet
Datasheet
Recommended PCNT Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422811
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7417783
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PCNT products
: "Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport." in: Nature communications, Vol. 10, Issue 1, pp. 428, (2019) (PubMed).: "Neurymenolide A, a Novel Mitotic Spindle Poison from the New Caledonian Rhodophyta Phacelocarpus neurymenioides." in: Marine drugs, Vol. 17, Issue 2, (2019) (PubMed).
: "Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region." in: Scientific reports, Vol. 9, Issue 1, pp. 2236, (2019) (PubMed).
: "Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis." in: Developmental cell, Vol. 50, Issue 2, pp. 229-246.e7, (2019) (PubMed).
: "The C7orf43/TRAPPC14 component links the TRAPPII complex to Rabin8 for preciliary vesicle tethering at the mother centriole during ciliogenesis." in: The Journal of biological chemistry, Vol. 294, Issue 42, pp. 15418-15434, (2019) (PubMed).
: "A LCMT1-PME-1 methylation equilibrium controls mitotic spindle size." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 12, pp. 1938-47, (2015) (PubMed).
: "Reduced cilia frequencies in human renal cell carcinomas versus neighboring parenchymal tissue." in: Cilia, Vol. 2, Issue 1, pp. 2, (2013) (PubMed).
: "Differing effects of herpes simplex virus 1 and pseudorabies virus infections on centrosomal function." in: Journal of virology, Vol. 87, Issue 12, pp. 7102-12, (2013) (PubMed).
: "Neuropeptide Y family receptors traffic via the Bardet-Biedl syndrome pathway to signal in neuronal primary cilia." in: Cell reports, Vol. 5, Issue 5, pp. 1316-29, (2013) (PubMed).
: "Development and distribution of neuronal cilia in mouse neocortex." in: The Journal of comparative neurology, Vol. 520, Issue 4, pp. 848-73, (2012) (PubMed).
Synonyms and alternative names related to PCNT
pericentrin (LOC100055203), Pericentrin-like protein (Plp), pericentrin (PCNT), pericentrin (pcnt), pericentrin (Pcnt), pericentrin (kendrin) (Pcnt), AKAP450, AW476095, C86676, CG6735, CG13459, CG18648, CG33957, CP309, Cp309, D-PLP, d-plp, DIP2A, Dmel\\CG33957, DPLP, Dplp, dPLP, dplp, KEN, kendrin, l(3)s2172, m239Asp, m275Asp, MOPD2, PACT, PCN, PCNT2, Pcnt2, PCNTB, PCTN2, PLP, Plp, pPlp, SCKL4Protein level used designations for PCNT
- CG33957-PC
- CG33957-PD
- CG33957-PF
- CG33957-PG
- CG33957-PH
- CG33957-PJ
- CG33957-PK
- CG33957-PL
- CG33957-PM
- CG33957-PN
- CG33957-PO
- CG33957-PP
- cp309-PC
- cp309-PD
- cp309-PF
- cp309-PG
- cp309-PH
- cp309-PJ
- cp309-PK
- cp309-PL
- cp309-PM
- cp309-PN
- cp309-PO
- cp309-PP
- drosophila pericentrin like protein
- lethal (3) s2172
- pericentrin
- pericentrin-like
- pericentrin-like protein
- pericentrin/AKAP450 centrosomal targeting
- kendrin
- pericentrin B
- pericentrin-2
- pericentrin-380
- pericentrin-B
- DIP2 disco-interacting protein 2 homolog A
- pericentrin (kendrin)
- pericentrin 2 (kendrin)
- pericentrin 2
- pericentrin-250
- pericentrin-360
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