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PCNA Products

(Proliferating Cell Nuclear Antigen (PCNA))

Categories

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008].

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Featured PCNA Categories

PCNA Antibodies

High quality antibodies with extensive validation data.

PCNA ELISA Kits

Reliable ELISA kits for a wide range of species.

PCNA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PCNA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
  • (6)
  • (6)
Cat. No. ABIN676583
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (5)
  • (6)
Cat. No. ABIN389344
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, IHC, ELISA, FACS
Validations
  • (2)
  • (7)
Cat. No. ABIN1724759
Quantity 100 μL
Datasheet Datasheet

Recommended PCNA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969612
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969611
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969610
Quantity 96 tests
Datasheet Datasheet

Recommended PCNA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314334
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314332
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN934965
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PCNA products

Li, Chai, Chang, Reng, Xue, Zhang, Lv, Hu: "A modified animal model of hepatic regeneration induced by hilar bile duct ligation." in: Scientific reports, Vol. 11, Issue 1, pp. 20201, (2022) (PubMed).

El-Rasikh, Farghali, Abdelrahman, Elgaffary, Abdelmalek, Emam, Ghoneim, Selim: "The implication of autoantibodies in early diagnosis and monitoring of plasmonic photothermal therapy in the treatment of feline mammary carcinoma." in: Scientific reports, Vol. 11, Issue 1, pp. 10441, (2021) (PubMed).

Mousa, Alhumaydhi, Abdellatif, Abdulmonem, AlKhowailed, Alsagaby, Al Rugaie, Alnuqaydan, Aljohani, Aljasir, Alwashmi, Soliman, Yosof, Elsheikh, Babiker, Alsuhaibani, Hegazy, Seleem: "Curcumin and ustekinumab cotherapy alleviates induced psoriasis in rats through their antioxidant, anti-inflammatory, and antiproliferative effects." in: Cutaneous and ocular toxicology, pp. 1-10, (2021) (PubMed).

Chen, Ren, Zhou, Deng, Hu, Zhang, Li: "HWL-088, a new potent free fatty acid receptor 1 (FFAR1) agonist, improves glucolipid metabolism and acts additively with metformin in ob/ob diabetic mice." in: British journal of pharmacology, Vol. 177, Issue 10, pp. 2286-2302, (2021) (PubMed).

Jiang, Ding, He, Li, Xu, Liu: "Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension." in: Clinical science (London, England : 1979), Vol. 135, Issue 21, pp. 2467-2481, (2021) (PubMed).

Li, Zong, Ye, Fu, Gu, Pan, Yang, Zhang, Zhou: "Pithecellobium clypearia: Amelioration Effect on Imiquimod-Induced Psoriasis in Mice Based on a Tissue Metabonomic Analysis." in: Frontiers in pharmacology, Vol. 12, pp. 748772, (2021) (PubMed).

Wang, Ma, Liang, Yang, Wei, Peng, Qiu, Lu, Zhu, Wang: "RCN1 induces sorafenib resistance and malignancy in hepatocellular carcinoma by activating c-MYC signaling via the IRE1α-XBP1s pathway." in: Cell death discovery, Vol. 7, Issue 1, pp. 298, (2021) (PubMed).

Yan, Liang, Fan, Zhou, Huang, Qi, Wang, Ma: "KAP1 silencing relieves OxLDL-induced vascular endothelial dysfunction by down-regulating LOX-1." in: Bioscience reports, Vol. 40, Issue 8, (2021) (PubMed).

Ruan, Yao, Li, Zhang, Yang, Sun, Li: "Effect of galectin-3 in the pathogenesis of arteriovenous fistula stenosis formation." in: Renal failure, Vol. 43, Issue 1, pp. 566-576, (2021) (PubMed).

Hong, Zhang, Xie, Jin, Zhang, Lu, Chen, Yu, Zhou, Chen, Yu, Sun: "The transcription factor Sox7 modulates endocardiac cushion formation contributed to atrioventricular septal defect through Wnt4/Bmp2 signaling." in: Cell death & disease, Vol. 12, Issue 4, pp. 393, (2021) (PubMed).

Synonyms and alternative names related to PCNA

proliferating cell nuclear antigen (PCNA), proliferating cell nuclear antigen (Pcna), proliferating cell nuclear antigen (pcna), DNA polymerase III sliding clamp (MMP_RS08810), proliferating cell nuclear antigen (ANI_1_512014), proliferating cell nuclear antigen (AOR_1_1500154), Proliferating cell nuclear antigen (PCNA), Proliferating cell nuclear antigen-like (MGC53867), proliferating cell nuclear antigen L homeolog (pcna.L), proliferating cell nuclear antigen 1 (pcna1), proliferating cell nuclear antigen (LOC106420145), Proliferating cell nuclear antigen (pcn1), 53/13, AO090003000846, cb16, CG9193, Dmel\\CG9193, DmPCNA, dPCNA, fb36g03, l(2)02448, l(2)56F, l(2)56Fa, l(2)s1534, MUS209, Mus209, pcna, PCNA, Pcna, pcna-A, Pcna/cyclin, PCNA/mus209, PCNAR, wu:fa28e03, wu:fb36g03

Protein level used designations for PCNA

  • DNA polymerase delta auxiliary protein
  • cyclin
  • proliferating cell nuclear antigen
  • CG9193-PA
  • CG9193-PB
  • Proliferating-cell-nuclear-antigen
  • mus209-PA
  • mus209-PB
  • proliferating-cell nuclear antigen
  • etID36690.10
  • fa28e03
  • proliferating cell nuclear antigen subtype1
  • proliferating cell nuclear antigen subtype2
  • proliferating cell nuclear antigen subtype3
  • CL1137_1
  • CL1137_1(454)
  • CL1137_1_ov
  • proliferative cell nuclear antigen
  • BnaA09g49520D
  • BnaC08g45280D
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