PCK1 Products
(phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))
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This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].
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Featured PCK1 Categories
PCK1 Antibodies
High quality antibodies with extensive validation data.
PCK1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PCK1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PCK1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), IF
Validations
- (8)
- (5)
Cat. No.
ABIN1882180
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, IF
Validations
- (1)
- (5)
Cat. No.
ABIN562129
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, IF
Validations
- (7)
Cat. No.
ABIN3022754
Quantity
100 μL
Datasheet
Datasheet
Recommended PCK1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958538
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969270
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958536
Quantity
96 tests
Datasheet
Datasheet
Recommended PCK1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314316
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN668008
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505500
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PCK1 products
: "Nuclear moonlighting of cytosolic glyceraldehyde-3-phosphate dehydrogenase regulates Arabidopsis response to heat stress." in: Nature communications, Vol. 11, Issue 1, pp. 3439, (2020) (PubMed).: "Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway." in: Journal of agricultural and food chemistry, Vol. 66, Issue 26, pp. 6772-6781, (2018) (PubMed).
: "Overexpression of PCK1 Gene Antagonizes Hepatocellular Carcinoma Through the Activation of Gluconeogenesis and Suppression of Glycolysis Pathways." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 47, Issue 1, pp. 344-355, (2018) (PubMed).
: "Nucleoporin-Regulated MAP Kinase Signaling in Immunity to a Necrotrophic Fungal Pathogen." in: Plant physiology, Vol. 172, Issue 2, pp. 1293-1305, (2017) (PubMed).
: "A metanephric adenoma of the kidney associated with polycythemia: A case report." in: Oncology letters, Vol. 11, Issue 1, pp. 352-354, (2016) (PubMed).
: "Temporal gene expression profiling of the rat knee joint capsule during immobilization-induced joint contractures." in: BMC musculoskeletal disorders, Vol. 16, pp. 125, (2015) (PubMed).
: "In utero exposure to the endocrine disruptor di-(2-ethylhexyl) phthalate induces long-term changes in gene expression in the adult male adrenal gland." in: Endocrinology, Vol. 155, Issue 5, pp. 1667-78, (2014) (PubMed).
: "Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 8, pp. 3339-50, (2014) (PubMed).
: "Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice." in: Nature medicine, Vol. 20, Issue 11, pp. 1263-9, (2014) (PubMed).
: "Ubiquitin-specific proteases UBP12 and UBP13 act in circadian clock and photoperiodic flowering regulation in Arabidopsis." in: Plant physiology, Vol. 162, Issue 2, pp. 897-906, (2014) (PubMed).
Synonyms and alternative names related to PCK1
phosphoenolpyruvate carboxykinase 1 (PCK1), phosphoenolpyruvate carboxykinase 2, mitochondrial (PCK2), phosphoenolpyruvate carboxykinase 2 (mitochondrial) (Pck2), phosphoenolpyruvate carboxykinase 1 (soluble) (pck1), phosphoenolpyruvate carboxykinase 1 S homeolog (pck1.S), phosphoenolpyruvate carboxykinase 1 (pck1), phosphoenolpyruvate carboxykinase, cytosolic [GTP] (LOC100634531), phosphoenolpyruvate carboxykinase 1, cytosolic (Pck1), phosphoenolpyruvate carboxykinase 1 (Pck1), phosphoenolpyruvate carboxylase 7 (pep7), phosphoenolpyruvate carboxykinase 2, mitochondrial (Pck2), Phosphoenolpyruvate carboxykinase (Pepck), phosphoenolpyruvate carboxylase (LOC107777405), phosphoenolpyruvate carboxykinase 1, cytosolic (pck1), 143299_at, 1810010O14Rik, 9130022B02Rik, AI265463, cb856, cb924, CG10924, CG17725, Dmel\\CG17725, dPEPCK, Dromel_CG17725_FBtr0086701_pepck_mORF, fj93h11, GTP, PCK, Pck-1, PCK1, PEPC, PEPCase, PEPCK, Pepck, pepck, PEPCK-C, pepck-c, PEPCK-M, PEPCK1, pepck1, PEPCK2, PEPCKC, pepckc, PHOSPHOENOLPYRUVATE CARBOXYKINASE, phosphoenolpyruvate carboxykinase 1, ppc, Ppc1C, PPCK1, RATPEPCK, T28I19.150, T28I19_150, wu:fc51c05, wu:fj93h11, zgc:63869Protein level used designations for PCK1
- PEP carboxykinase
- phosphoenolpyruvate carboxykinase, cytosolic
- phosphoenolpyruvate carboxykinase, cytosolic [GTP]
- phosphoenolpyruvate carboxylase
- phosphopyruvate carboxylase
- phosphoenolpyruvate carboxykinase [GTP], mitochondrial
- PEPCK
- phosphoenolpyruvate carboxykinase 1 (soluble)
- PEPCK-C
- Phosphoenolpyruvate carboxykinase, cytosolic
- Phosphoenolpyruvate carboxykinase 1 (soluble)-like
- phosphoenolpyruvate carboxykinase (GTP)
- phosphoenolpyruvate carboxykinase 1, cytosolic
- phosphoenolpyruvate carboxykinase, cytosolic (GTP)
- cytosolic phosphoenolpyruvate carboxykinase
- gluconeogenic enzyme
- phosphoenolpyruvate carboxykinase 1 variant 1
- phosphoenolpyruvate carboxykinase 1 variant 2
- phosphoenolpyruvate carboxykinase 1 variant 3
- phosphoenolpyruvate carboxykinase 1 variant 4
- phosphoenolpyruvate carboxykinase 1 variant 5
- CL1793_1
- CL1793_1_ov
- Ppc1
- pMR15
- pep*-pepcZm2A
- pep8
- synonymous gene name: Pep2 in maize linkage map
- CG17725-PA
- CG17725-PB
- Pepck-PA
- Pepck-PB
- Phosphoenolpyruvate-carboxykinase
- phosphoenol pyruvate carboxykinase
- phosphoenolpyruvate carboxy kinase
- phosphoenolpyruvate carboxykinase
- cytosolic phosphoenolpyruvate carboxykinase 1
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