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PCDHGB2 Products

(Protocadherin gamma Subfamily B, 2 (PCDHGB2))
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008].

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Featured PCDHGB2 Categories

PCDHGB2 Antibodies

High quality antibodies with extensive validation data.

PCDHGB2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PCDHGB2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN565980
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1539095
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN565979
Quantity 50 μL
Datasheet Datasheet

Recommended PCDHGB2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314264
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314266
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2728396
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our PCDHGB2 products

Lobas, Helsper, Vernon, Schreiner, Zhang, Holtzman, Thedens, Weiner: "Molecular heterogeneity in the choroid plexus epithelium: the 22-member ?-protocadherin family is differentially expressed, apically localized, and implicated in CSF regulation." in: Journal of neurochemistry, Vol. 120, Issue 6, pp. 913-27, (2012) (PubMed).

Prasad, Weiner: "Direct and Indirect Regulation of Spinal Cord Ia Afferent Terminal Formation by the ?-Protocadherins." in: Frontiers in molecular neuroscience, Vol. 4, pp. 54, (2012) (PubMed).

Synonyms and alternative names related to PCDHGB2

protocadherin gamma subfamily B, 2 (PCDHGB2), protocadherin gamma subfamily B, 2 (Pcdhgb2), PCDH-GAMMA-B2

Protein level used designations for PCDHGB2

  • protocadherin gamma-B2
  • 3' RACE product
  • protocadherin gamma B2
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