p63 Products
(Tumor Protein P63 (TP63))
Categories
This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3)\; split-hand/foot malformation 4 (SHFM4)\; ankyloblepharon-ectodermal defects-cleft lip/palate\; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth)\; limb-mammary syndrome\; Rap-Hodgkin syndrome (RHS)\; and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008].
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Featured p63 Categories
p63 Antibodies
High quality antibodies with extensive validation data.
p63 ELISA Kits
Reliable ELISA kits for a wide range of species.
p63 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended p63 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ICC, IF, IP, IHC (p), IHC (fro), PLA
Validations
- (8)
- (8)
Cat. No.
ABIN2855394
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN3023012
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, Coat
Validations
- (4)
Cat. No.
ABIN6940965
Quantity
100 μg
Datasheet
Datasheet
Recommended p63 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971006
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960310
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960311
Quantity
96 tests
Datasheet
Datasheet
Recommended p63 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1323400
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125563
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323402
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our p63 products
: "Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin." in: Aging cell, Vol. 19, Issue 3, pp. e13072, (2020) (PubMed).: "TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment." in: Cell stem cell, Vol. 24, Issue 2, pp. 271-284.e8, (2020) (PubMed).
: "Cytological Immunostaining of HMGA2, LRP1B, and TP63 as Potential Biomarkers for Triaging Human Papillomavirus-Positive Women." in: Translational oncology, Vol. 12, Issue 7, pp. 959-967, (2019) (PubMed).
: "A revised airway epithelial hierarchy includes CFTR-expressing ionocytes. ..." in: Nature, Vol. 560, Issue 7718, pp. 319-324, (2019) (PubMed).
: "PAX9 regulates squamous cell differentiation and carcinogenesis in the oro-oesophageal epithelium." in: The Journal of pathology, Vol. 244, Issue 2, pp. 164-175, (2019) (PubMed).
: "Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner." in: PLoS pathogens, Vol. 14, Issue 12, pp. e1007457, (2019) (PubMed).
: "Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury." in: Cell stem cell, Vol. 22, Issue 5, pp. 668-683.e6, (2018) (PubMed).
: "Fibroblast Growth Factor Receptor 2 (FGFR2) Is Required for Meibomian Gland Homeostasis in the Adult Mouse." in: Investigative ophthalmology & visual science, Vol. 58, Issue 5, pp. 2638-2646, (2017) (PubMed).
: "A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease." in: Nature microbiology, Vol. 2, pp. 16196, (2016) (PubMed).
: "Primary urinary bladder adenosquamous carcinoma complicated with lower limb deep venous thromboses: a case report." in: International journal of clinical and experimental pathology, Vol. 7, Issue 12, pp. 9032-7, (2015) (PubMed).
Synonyms and alternative names related to p63
tumor protein p63 (TP63), tumor protein p63 (tp63), tumor protein p63 (Tp63), transformation related protein 63 (Trp63), tumor protein p63 L homeolog (tp63.L), AI462811, AIS, B(p51A), B(p51B), DNp63, EEC3, id:ibd3516, KET, Ket, ket, LMS, NBP, np63, OFC8, p40, p51, P51/P63, p53CP, p63, P63, p73H, p73L, P73l, RHS, SHFM4, TP53CP, TP53L, TP63, tp63, Tp63, TP73L, tp73l, Tp73l, tp73l-A, Trp53rp1, Trp63, TRP63, trp63, wu:fc89f04, wu:fk85h07, wu:fk88b02, Xp63Protein level used designations for p63
- CUSP
- amplified in squamous cell carcinoma
- chronic ulcerative stomatitis protein
- keratinocyte transcription factor KET
- transformation-related protein 63
- tumor protein 63
- tumor protein p53-competing protein
- tumor protein p63 deltaN isoform delta
- tumor protein p63
- delta-Np63
- fc89f04
- transformation related protein 63
- tumor protein 63 kDa
- tumor protein 63-like
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