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p53 Proteins

(Tumor Protein P53 (TP53))

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].

recommended

p53 Protein (AA 1-393) (GST tag) (ABIN1323380)

TP53 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

p53 Protein (His tag) (ABIN2669713)

TP53 Origin: Human Host: Escherichia coli (E. coli) Recombinant STD, PI, in vitro Active

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recommended

p53 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2734068)

TP53 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining STD, AbP

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p53 Proteins by Origin

Find p53 Proteins for a variety of species such as anti-Human p53, anti-Mouse p53, anti-Rat p53. The species listed below are among those available. Click on a link to go to the corresponding products.

p53 Proteins by Source

Here you will find p53 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

p53 Proteins by Protein Type

Here you can find p53 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

p53 Proteins by Application

Find p53 Proteins validated for a specific application such as ELISA, WB, SDS, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

p53 Proteins by Biological Activity

Find p53 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular p53 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

p53 Protein (AA 1-393) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1323380

Quantity 10 μg

Datasheet Datasheet

p53 Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2669713

Quantity 10 μg

Datasheet Datasheet

p53 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2734068

Quantity 20 μg

Datasheet Datasheet

p53 Protein (AA 1-391) (His tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7125562

Quantity 50 μg

Datasheet Datasheet

p53 Protein (AA 94-201) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1323382

Quantity 10 μg

Datasheet Datasheet

p53 Protein (His-SUMO Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1046803

Quantity 100 μg

Datasheet Datasheet

p53 Protein (AA 1-386) (His tag)

Reactivity Cow

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7504911

Quantity 100 μg

Datasheet Datasheet

p53 Protein (AA 1-390) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7411480

Quantity 100 μg

Datasheet Datasheet

p53 Protein (AA 90-354) (His tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7392743

Quantity 100 μg

Datasheet Datasheet

p53 Protein

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2131006

Quantity 100 μg

Datasheet Datasheet

p53 Protein (AA 134-387) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7392740

Quantity 100 μg

Datasheet Datasheet

p53 Protein (AA 133-393) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7424587

Quantity 100 μg

Datasheet Datasheet

p53 Protein (AA 108-370) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7392737

Quantity 100 μg

Datasheet Datasheet

p53 Protein (AA 1-393) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7424497

Quantity 100 μg

Datasheet Datasheet

p53 Protein (AA 25-305, Tetramer) (PE)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7504498

Quantity 100 μg

Datasheet Datasheet

Latest Publications for our p53 Proteins

El-Rasikh, Farghali, Abdelrahman, Elgaffary, Abdelmalek, Emam, Ghoneim, Selim: "The implication of autoantibodies in early diagnosis and monitoring of plasmonic photothermal therapy in the treatment of feline mammary carcinoma." in: Scientific reports, Vol. 11, Issue 1, pp. 10441, (2021) (PubMed).

Li, Xia, Su, Qin, Chen, Li, Dong, Ding, Li, Huang, Ge, Hou, Wang, Sun, Bai, Shen, Fang, Liu, Zhang, Zhang, Zhang, Shao: "Species-specific mutual regulation of p53 and miR-138 between human, rat and mouse." in: Scientific reports, Vol. 6, pp. 26187, (2016) (PubMed).

Lebedev, Nemajerova, Foda, Kornaj, Tong, Moll, Seeliger: "A Novel In Vitro CypD-Mediated p53 Aggregation Assay Suggests a Model for Mitochondrial Permeability Transition by Chaperone Systems." in: Journal of molecular biology, Vol. 428, Issue 20, pp. 4154-4167, (2016) (PubMed).

Zhang, Zhong, Chen: "LC-MS/MS-based targeted proteomics quantitatively detects the interaction between p53 and MDM2 in breast cancer." in: Journal of proteomics, Vol. 152, pp. 172-180, (2016) (PubMed).

Lacombe, Mangé, Bougnoux, Prassas, Solassol: "A multiparametric serum marker panel as a complementary test to mammography for the diagnosis of node-negative early-stage breast cancer and DCIS in young women." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 23, Issue 9, pp. 1834-42, (2014) (PubMed).

Huang, Jeong, Okamura, Sook-Kim, Zhu, Guerrero-Preston, Ratovitski: "Global tumor protein p53/p63 interactome: making a case for cisplatin chemoresistance." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 12, pp. 2367-79, (2012) (PubMed).

Lamb, Crawford: "Characterization of the human p53 gene." in: Molecular and cellular biology, Vol. 6, Issue 5, pp. 1379-85, (1987) (PubMed).

Zakut-Houri, Bienz-Tadmor, Givol, Oren: "Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells." in: The EMBO journal, Vol. 4, Issue 5, pp. 1251-5, (1985) (PubMed).

Harlow, Williamson, Ralston, Helfman, Adams: "Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53." in: Molecular and cellular biology, Vol. 5, Issue 7, pp. 1601-10, (1985) (PubMed).

Aliases for p53 Proteins

tumor protein p53 (TP53) Proteins
cellular tumor antigen p53 (CpipJ_CPIJ002758) Proteins
tumor protein p53 (Tp53) Proteins
tumor protein p53 (tp53) Proteins
transformation related protein 53 (Trp53) Proteins
tumor protein p53 L homeolog (tp53.L) Proteins
bbl Proteins
BCC7 Proteins
bfy Proteins
bhy Proteins
brp53 Proteins
drp53 Proteins
etID22686.5 Proteins
fb40d06 Proteins
LFS1 Proteins
p44 Proteins
P53 Proteins
p53 Proteins
Tp53 Proteins
tp53 Proteins
TP53 Proteins
TRP53 Proteins
Trp53 Proteins
wu:fb40d06 Proteins
Xp53 Proteins
zgc:111919 Proteins

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p53 Proteins by Origin

p53 Proteins by Source

p53 Proteins by Protein Type

p53 Proteins by Application

p53 Proteins by Biological Activity

Popular p53 Proteins

Latest Publications for our p53 Proteins

Aliases for p53 Proteins

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