P4HTM Products
(Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
Categories
The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Featured P4HTM Categories
P4HTM Antibodies
High quality antibodies with extensive validation data.
P4HTM Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended P4HTM Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Bat, Cow, Dog, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6744213
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6741725
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN527161
Quantity
100 μg
Datasheet
Datasheet
Recommended P4HTM Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313840
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3118601
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3124637
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our P4HTM products
: "PHD4 stimulates tumor angiogenesis in osteosarcoma cells via TGF-α." in: Molecular cancer research : MCR, Vol. 11, Issue 11, pp. 1337-48, (2013) (PubMed).: "Prolyl hydroxylases 2 and 3 act in gliomas as protective negative feedback regulators of hypoxia-inducible factors." in: Cancer research, Vol. 70, Issue 1, pp. 357-66, (2010) (PubMed).
: "Peroxisomal localization of hypoxia-inducible factors and hypoxia-inducible factor regulatory hydroxylases in primary rat hepatocytes exposed to hypoxia-reoxygenation." in: The American journal of pathology, Vol. 169, Issue 4, pp. 1251-69, (2006) (PubMed).
: "Oxygen sensors and angiogenesis." in: Seminars in cell & developmental biology, Vol. 13, Issue 1, pp. 29-37, (2002) (PubMed).
: "Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 21, pp. 13459-64, (2002) (PubMed).
: "A conserved family of prolyl-4-hydroxylases that modify HIF." in: Science (New York, N.Y.), Vol. 294, Issue 5545, pp. 1337-40, (2001) (PubMed).
Synonyms and alternative names related to P4HTM
prolyl 4-hydroxylase, transmembrane (P4htm), prolyl 4-hydroxylase, transmembrane (P4HTM), prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), shisa family member 5 (SHISA5), 4933406E20Rik, AI853847, BB128974, EGLN4, HIFPH4, P4H-TM, Ph-4, PH-4, PH4, PHD4, RGD1311848Protein level used designations for P4HTM
- hypoxia-inducible factor prolyl 4-hydroxylase
- transmembrane prolyl 4-hydroxylase
- HIF-PH4
- HIF-prolyl hydroxylase 4
- HPH-4
- P4H with transmembrane domain
- Prolyl hydroxlase domain-containing 4
- hypoxia inducible factor prolyl 4 hydroxylase
- hypoxia-inducible factor prolyl hydroxylase 4
- proline 4-hydroxylase
- P4H-TM
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