P4HA2 Products
(Prolyl 4-Hydroxylase, alpha Polypeptide II (P4HA2))
Categories
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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Featured P4HA2 Categories
P4HA2 Antibodies
High quality antibodies with extensive validation data.
P4HA2 ELISA Kits
Reliable ELISA kits for a wide range of species.
P4HA2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended P4HA2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ELISA
Validations
- (4)
Cat. No.
ABIN7164785
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN1681193
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7435769
Quantity
100 μL
Datasheet
Datasheet
Recommended P4HA2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969622
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958834
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1150196
Quantity
96 tests
Datasheet
Datasheet
Recommended P4HA2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313834
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397951
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2728092
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our P4HA2 products
: "Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts." in: The Journal of biological chemistry, Vol. 288, Issue 15, pp. 10819-29, (2013) (PubMed).: "Collagen prolyl hydroxylases are essential for breast cancer metastasis." in: Cancer research, Vol. 73, Issue 11, pp. 3285-96, (2013) (PubMed).
: "Defective p53 antiangiogenic signaling in glioblastoma." in: Neuro-oncology, Vol. 12, Issue 9, pp. 894-907, (2010) (PubMed).
Synonyms and alternative names related to P4HA2
prolyl 4-hydroxylase subunit alpha 2 (P4HA2), prolyl 4-hydroxylase, alpha polypeptide II (P4HA2), procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide (P4ha2), prolyl 4-hydroxylase subunit alpha 2 (P4ha2), AA407196, C76437, P4hlProtein level used designations for P4HA2
- prolyl 4-hydroxylase subunit alpha-2
- procollagen-proline, 2-oxoglutarate 4-dioxygenase, alpha polypeptide II, isoform 1
- prolyl 4-hydroxylase, alpha II subunit
- prolyl 4-hydroxylase, alpha polypeptide II
- prolyl 4-hydroxylase subunit alpha-2-like
- 4-PH alpha-2
- Prolyl 4-hydroxylase alpha IIa subunit
- procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2
- 4-PH alpha 2
- C-P4Halpha(II)
- collagen prolyl 4-hydroxylase alpha(II)
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide
- prolyl 4-hydroxylase alpha-2 subunit
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