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P2RY12 Products

(Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Categories

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. [provided by RefSeq, Jul 2008].

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Featured P2RY12 Categories

P2RY12 Antibodies

High quality antibodies with extensive validation data.

P2RY12 ELISA Kits

Reliable ELISA kits for a wide range of species.

P2RY12 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended P2RY12 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, Neut, FACS
Validations
  • (5)
Cat. No. ABIN5611346
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF (cc)
Validations
  • (4)
Cat. No. ABIN1387659
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7075321
Quantity 100 μL
Datasheet Datasheet

Recommended P2RY12 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969784
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958996
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN511471
Quantity 96 tests
Datasheet Datasheet

Recommended P2RY12 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408405
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Mammalian Cells
Validations
Cat. No. ABIN7538496
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3118050
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our P2RY12 products

Lim, Hainsworth, Mohan, Chaurasia: "Characterization of a functionally active primary microglial cell culture from the pig retina." in: Experimental eye research, Vol. 185, pp. 107670, (2019) (PubMed).

Walker, Lue, Beach, Tooyama: "Microglial Phenotyping in Neurodegenerative Disease Brains: Identification of Reactive Microglia with an Antibody to Variant of CD105/Endoglin." in: Cells, Vol. 8, Issue 7, (2019) (PubMed).

Morin-Brureau, Milior, Royer, Chali, LeDuigou, Savary, Blugeon, Jourdren, Akbar, Dupont, Navarro, Baulac, Bielle, Mathon, Clemenceau, Miles: "Microglial phenotypes in the human epileptic temporal lobe." in: Brain : a journal of neurology, Vol. 141, Issue 12, pp. 3343-3360, (2018) (PubMed).

Garcia-Mesa, Jay, Checkley, Luttge, Dobrowolski, Valadkhan, Landreth, Karn, Alvarez-Carbonell: "Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system." in: Journal of neurovirology, Vol. 23, Issue 1, pp. 47-66, (2016) (PubMed).

Bornø, Ploug, Bune, Rosenmeier, Thaning: "Purinergic receptors expressed in human skeletal muscle fibres." in: Purinergic signalling, Vol. 8, Issue 2, pp. 255-64, (2012) (PubMed).

Neves, Radke, Weller: "Cysteinyl leukotrienes acting via granule membrane-expressed receptors elicit secretion from within cell-free human eosinophil granules." in: The Journal of allergy and clinical immunology, Vol. 125, Issue 2, pp. 477-82, (2010) (PubMed).

Savi, Zachayus, Delesque-Touchard, Labouret, Hervé, Uzabiaga, Pereillo, Culouscou, Bono, Ferrara, Herbert: "The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 29, pp. 11069-74, (2006) (PubMed).

Abbracchio, Burnstock: "Purinoceptors: are there families of P2X and P2Y purinoceptors?" in: Pharmacology & therapeutics, Vol. 64, Issue 3, pp. 445-75, (1995) (PubMed).

Synonyms and alternative names related to P2RY12

purinergic receptor P2Y, G-protein coupled 12 (P2ry12), purinergic receptor P2Y12 (P2RY12), purinergic receptor P2Y12 (P2ry12), 2900079B22Rik, 4921504D23Rik, ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, P2y12, SP1999

Protein level used designations for P2RY12

  • P2Y purinoceptor 12
  • ADP-glucose receptor
  • G-protein coupled receptor SP1999
  • Gi-coupled ADP receptor HORK3
  • P2Y12 platelet ADP receptor
  • purinergic receptor P2RY12
  • putative G-protein coupled receptor
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