P2RX7 Products
(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
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The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010].
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Featured P2RX7 Categories
P2RX7 Antibodies
High quality antibodies with extensive validation data.
P2RX7 ELISA Kits
Reliable ELISA kits for a wide range of species.
P2RX7 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended P2RX7 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS
Validations
- (6)
Cat. No.
ABIN5542663
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN2855803
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN651861
Quantity
400 μL
Datasheet
Datasheet
Recommended P2RX7 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969783
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958994
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1146777
Quantity
96 tests
Datasheet
Datasheet
Recommended P2RX7 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7491711
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313816
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN6964308
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our P2RX7 products
: "Pannexin 3 activates P2X7 receptor to mediate inflammation and cartilage matrix degradation in temporomandibular joint osteoarthritis." in: Cell biology international, Vol. 47, Issue 7, pp. 1183-1197, (2023) (PubMed).: "ATP in the tumour microenvironment drives expression of nfP2X7, a key mediator of cancer cell survival." in: Oncogene, Vol. 38, Issue 2, pp. 194-208, (2019) (PubMed).
: "P2RX7 Deletion in T Cells Promotes Autoimmune Arthritis by Unleashing the Tfh Cell Response." in: Frontiers in immunology, Vol. 10, pp. 411, (2019) (PubMed).
: "New role of P2X7 receptor in an Alzheimer's disease mouse model." in: Molecular psychiatry, Vol. 24, Issue 1, pp. 108-125, (2019) (PubMed).
: "TCR-pMHC encounter differentially regulates transcriptomes of tissue-resident CD8 T cells." in: European journal of immunology, Vol. 48, Issue 1, pp. 128-150, (2018) (PubMed).
: "P2X7 receptor in spinal tuberculosis: Gene polymorphisms and protein levels in Chinese Han population." in: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, Vol. 57, pp. 138-144, (2017) (PubMed).
: "P2X7 receptor-dependent tuning of gut epithelial responses to infection." in: Immunology and cell biology, Vol. 95, Issue 2, pp. 178-188, (2016) (PubMed).
: "P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation." in: International journal of molecular medicine, Vol. 35, Issue 5, pp. 1179-88, (2015) (PubMed).
: "P2X7 Receptor Antagonism Attenuates the Intermittent Hypoxia-induced Spatial Deficits in a Murine Model of Sleep Apnea Via Inhibiting Neuroinflammation and Oxidative Stress." in: Chinese medical journal, Vol. 128, Issue 16, pp. 2168-75, (2015) (PubMed).
: "Lidocaine preferentially inhibits the function of purinergic P2X7 receptors expressed in Xenopus oocytes." in: Anesthesia and analgesia, Vol. 120, Issue 3, pp. 597-605, (2015) (PubMed).
Synonyms and alternative names related to P2RX7
purinergic receptor P2X 7 (P2RX7), purinergic receptor P2X, ligand-gated ion channel, 7 (p2rx7), P2X purinoceptor 7 (LOC100458463), purinergic receptor P2X, ligand-gated ion channel, 7 (P2rx7), purinergic receptor P2X 7 (P2rx7), AI467586, P2RX7, P2X(7), P2X7, p2x7, P2X7R, p2xr7Protein level used designations for P2RX7
- P2X purinoceptor 7
- purinergic receptor P2X, ligand-gated ion channel, 7
- p2X purinoceptor 7-like
- ATP receptor
- P2X7 receptor
- P2Z receptor
- purinergic receptor P2X7 variant A
- P2X7 purinoceptor
- purinergic receptor P2X7
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