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p130 Proteins

(Retinoblastoma-Like 2 (p130) (RBL2))

Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.

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p130 Protein (Myc-DYKDDDDK Tag) (ABIN2730602)

RBL2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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p130 Proteins by Origin

Find p130 Proteins for a variety of species such as anti-Human p130. The species listed below are among those available. Click on a link to go to the corresponding products.

p130 Proteins by Source

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p130 Proteins by Protein Type

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p130 Proteins by Application

Find p130 Proteins validated for a specific application such as AbP, STD. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular p130 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

p130 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2730602

Quantity 20 μg

Datasheet Datasheet

Aliases for p130 Proteins

retinoblastoma-like 2 (p130) (RBL2) Proteins
RB transcriptional corepressor like 2 (RBL2) Proteins
related to retinoblastoma 2 (LOC541652) Proteins
RB transcriptional corepressor like 2 (Rbl2) Proteins
p130 Proteins
P130 Proteins
PRB2 Proteins
Rb2 Proteins
RBL2 Proteins
RBR-2 Proteins
RBR2 Proteins
RRB2a Proteins

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