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PAX6 Products

(Paired Box 6 (PAX6))

Categories

This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012].

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Featured PAX6 Categories

PAX6 Antibodies

High quality antibodies with extensive validation data.

PAX6 ELISA Kits

Reliable ELISA kits for a wide range of species.

PAX6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PAX6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (6)
Cat. No. ABIN5542664
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, FACS, IHC (p), IF (p), IHC (fro)
Validations
  • (5)
Cat. No. ABIN1387454
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IF, IHC (p)
Validations
  • (5)
Cat. No. ABIN652261
Quantity 400 μL
Datasheet Datasheet

Recommended PAX6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958371
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975711
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674916
Quantity 96 tests
Datasheet Datasheet

Recommended PAX6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1314075
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124297
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314077
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PAX6 products

Liu, Novak, Pepin, Maschhoff, Worner, Chen, Zhang, Hu: "A congenital hydrocephalus-causing mutation in Trim71 induces stem cell defects via inhibiting Lsd1 mRNA translation." in: EMBO reports, Vol. 24, Issue 2, pp. e55843, (2023) (PubMed).

Filippello, Urbano, Di Mauro, Scamporrino, Di Pino, Scicali, Rabuazzo, Purrello, Piro: "Chronic Exposure to Palmitate Impairs Insulin Signaling in an Intestinal L-cell Line: A Possible Shift from GLP-1 to Glucagon Production." in: International journal of molecular sciences, Vol. 19, Issue 12, (2019) (PubMed).

Suriano, Bodznick: "Evidence for generative homology of cerebellum and cerebellum-like structures in an elasmobranch fish based on Pax6, Cbln1 and Grid2 expression." in: The Journal of comparative neurology, Vol. 526, Issue 14, pp. 2187-2203, (2018) (PubMed).

Gao, Yourick, Sprando: "Generation of nine induced pluripotent stem cell lines as an ethnic diversity panel." in: Stem cell research, Vol. 31, pp. 193-196, (2018) (PubMed).

Pastor, Liu, Chen, Ho, Kim, Hunt, Lukianchikov, Liu, Polo, Jacobsen, Clark: "TFAP2C regulates transcription in human naive pluripotency by opening enhancers." in: Nature cell biology, Vol. 20, Issue 5, pp. 553-564, (2018) (PubMed).

Zhang, Xu, Xu, Wei, Xu: "Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation." in: Cell proliferation, Vol. 49, Issue 5, pp. 589-98, (2017) (PubMed).

Zhang, Xu, Xu, Wei, Xu: "Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition." in: Human reproduction (Oxford, England), Vol. 31, Issue 4, pp. 832-43, (2016) (PubMed).

Xu, Zhang, Xu, Wei, Xu: "Sensitivity of human embryonic stem cells to different conditions during cryopreservation." in: Cryobiology, Vol. 71, Issue 3, pp. 486-92, (2016) (PubMed).

Imberti, Tomasoni, Ciampi, Pezzotta, Derosas, Xinaris, Rizzo, Papadimou, Novelli, Benigni, Remuzzi, Morigi: "Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury." in: Scientific reports, Vol. 5, pp. 8826, (2015) (PubMed).

Wen, Jin: "Production of neural stem cells from human pluripotent stem cells." in: Journal of biotechnology, Vol. 188, pp. 122-9, (2015) (PubMed).

Synonyms and alternative names related to PAX6

paired box 6 (PAX6), paired box 6 (pax6), paired box 6 (Pax6), paired box 6 L homeolog (pax6.L), paired box 6 S homeolog (pax6.S), paired box 6a (pax6a), 1500038E17Rik, AEY11, AN, an2, AN2, cb280, D11S812E, Dey, fc20e07, Gsfaey11, MGC52531, mgda, MGDA, pax-6, PAX-6, Pax-6, pax-a, pax6, Pax6.1, pax6a, pax6b, PAXZF-A, paxzfa, pax[zf-a], Sey, wagr, WAGR, wu:fc20e07, XLPAX6, xpax6, zfpax-6a, zfpax-6b

Protein level used designations for PAX6

  • paired box protein Pax-6
  • paired box 6
  • paired box gene 6
  • oculorhombin
  • paired box homeotic gene 6
  • paired box gene 6 a
  • aniridia type II protein
  • paired box homeotic gene-6
  • paired box gene 6 (aniridia, keratitis)
  • paired box protein PAX6
  • paired box gene 6 b
  • paired domain transcription factor variant B
  • paired-type homeodomain Pax-6 protein
  • Dickie's small eye
  • small eye
  • etID309716.25
  • paired box protein Pax[Zf-a]
  • pax-6
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