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PAWR Products

(PRKC, Apoptosis, WT1, Regulator (PAWR))
The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells. [provided by RefSeq, Jul 2008].

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Featured PAWR Categories

PAWR Antibodies

High quality antibodies with extensive validation data.

PAWR ELISA Kits

Reliable ELISA kits for a wide range of species.

PAWR Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PAWR Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7010306
Quantity 60 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6264442
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7101749
Quantity 20 μL
Datasheet Datasheet

Recommended PAWR ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969503
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958728
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381452
Quantity 96 tests
Datasheet Datasheet

Recommended PAWR Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314060
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2728222
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our PAWR products

Thayyullathil, Rahman, Pallichankandy, Patel, Galadari et al.: "ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death in human malignant ..." in: FEBS open bio, Vol. 4, pp. 763-76, (2014) (PubMed).

Chakraborty, Qiu, Vasudevan, Rangnekar: "Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression." in: Cancer research, Vol. 61, Issue 19, pp. 7255-63, (2001) (PubMed).

Chang, Kim, Shin: "p62 forms a ternary complex with PKCzeta and PAR-4 and antagonizes PAR-4-induced PKCzeta inhibition." in: FEBS letters, Vol. 510, Issue 1-2, pp. 57-61, (2001) (PubMed).

Johnstone, See, Sells, Wang, Muthukkumar, Englert, Haber, Licht, Sugrue, Roberts, Rangnekar, Shi: "A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1." in: Molecular and cellular biology, Vol. 16, Issue 12, pp. 6945-56, (1997) (PubMed).

Synonyms and alternative names related to PAWR

pro-apoptotic WT1 regulator (PAWR), PRKC, apoptosis, WT1, regulator L homeolog (pawr.L), PRKC, apoptosis, WT1, regulator (pawr), pro-apoptotic WT1 regulator (Pawr), PRKC, apoptosis, WT1, regulator (Pawr), 2310001G03Rik, MGC81382, Par-4, PAR4, Par4, PAWR, pawrl, zgc:103513

Protein level used designations for PAWR

  • PRKC, apoptosis, WT1, regulator
  • PAR-4
  • PRKC apoptosis WT1 regulator protein
  • PRKC, apoptosis, WT1, regulator like
  • WT1-interacting protein
  • prostate apoptosis response 4 protein
  • prostate apoptosis response protein 4
  • prostate apoptosis response protein PAR-4
  • prostate apoptosis response-4
  • transcriptional repressor PAR4
  • Prostate apoptosis response protein 4
  • par-4 induced by effectors of apoptosis
  • transcriptional repressor Par-4-like protein PAWR
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