PATZ1 Products
(Zinc Finger Protein 278 (ZNF278))
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The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated t1\;22p36.1\;q12. The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008].
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Featured PATZ1 Categories
PATZ1 Antibodies
High quality antibodies with extensive validation data.
PATZ1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PATZ1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN525299
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
Validations
- (4)
Cat. No.
ABIN2779693
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (4)
Cat. No.
ABIN2780922
Quantity
100 μL
Datasheet
Datasheet
Recommended PATZ1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314058
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314057
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3085597
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PATZ1 products
: "Transcription factors with conserved binding sites near ATOH1 on the POU4F3 gene enhance the induction of cochlear hair cells." in: Molecular neurobiology, Vol. 51, Issue 2, pp. 672-84, (2015) (PubMed).Synonyms and alternative names related to PATZ1
POZ/BTB and AT hook containing zinc finger 1 (PATZ1), POZ/BTB and AT hook containing zinc finger 1 S homeolog (patz1.S), POZ (BTB) and AT hook containing zinc finger 1 (Patz1), POZ-, AT hook-, and zinc finger-containing protein 1 (LOC100153931), 8430401L15Rik, AI447519, dJ400N23, MAZR, Mazr, PATZ, Patz, RIAZ, ZBTB19, Zfp278, ZNF278, Znf278, ZSGProtein level used designations for PATZ1
- zinc finger protein 278
- BTB-POZ domain zinc finger transcription factor
- BTB/POZ domain zinc finger transcription factor
- MAZ-related factor
- POZ-, AT hook-, and zinc finger-containing protein 1
- POZ-AT hook-zinc finger protein
- protein kinase A RI subunit alpha-associated protein
- zinc finger and BTB domain-containing protein 19
- zinc finger sarcoma gene protein
- POZ and AT hook containing zinc finger 1 long C isoform
- transcription factor (MAZ-related) MAZR
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