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PATZ1 Products

(Zinc Finger Protein 278 (ZNF278))

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The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated t1\;22p36.1\;q12. The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008].

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Featured PATZ1 Categories

PATZ1 Antibodies

High quality antibodies with extensive validation data.

PATZ1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PATZ1 Antibodies

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Reactivity
Application
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Cat. No.
Quantity
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Reactivity Human
Application WB, ELISA
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Cat. No. ABIN525299
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
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  • (4)
Cat. No. ABIN2779693
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
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Cat. No. ABIN2780922
Quantity 100 μL
Datasheet Datasheet

Recommended PATZ1 Proteins

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Source
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Quantity
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Reactivity Human
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Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
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Cat. No. ABIN1314057
Quantity 25 μg
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Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3085597
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Latest Publications for our PATZ1 products

Ikeda, Pak, Chavez, Ryan: "Transcription factors with conserved binding sites near ATOH1 on the POU4F3 gene enhance the induction of cochlear hair cells." in: Molecular neurobiology, Vol. 51, Issue 2, pp. 672-84, (2015) (PubMed).

Synonyms and alternative names related to PATZ1

POZ/BTB and AT hook containing zinc finger 1 (PATZ1), POZ/BTB and AT hook containing zinc finger 1 S homeolog (patz1.S), POZ (BTB) and AT hook containing zinc finger 1 (Patz1), POZ-, AT hook-, and zinc finger-containing protein 1 (LOC100153931), 8430401L15Rik, AI447519, dJ400N23, MAZR, Mazr, PATZ, Patz, RIAZ, ZBTB19, Zfp278, ZNF278, Znf278, ZSG

Protein level used designations for PATZ1

  • zinc finger protein 278
  • BTB-POZ domain zinc finger transcription factor
  • BTB/POZ domain zinc finger transcription factor
  • MAZ-related factor
  • POZ-, AT hook-, and zinc finger-containing protein 1
  • POZ-AT hook-zinc finger protein
  • protein kinase A RI subunit alpha-associated protein
  • zinc finger and BTB domain-containing protein 19
  • zinc finger sarcoma gene protein
  • POZ and AT hook containing zinc finger 1 long C isoform
  • transcription factor (MAZ-related) MAZR
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