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PARP1 Products

(Poly (ADP-Ribose) Polymerase 1 (PARP1))

Categories

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008].

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Featured PARP1 Categories

PARP1 Antibodies

High quality antibodies with extensive validation data.

PARP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PARP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PARP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP, IF, ICC, IHC (p), ChIP
Validations
  • (7)
  • (17)
Cat. No. ABIN2854798
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (2)
  • (8)
Cat. No. ABIN6145232
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, IHC (p)
Validations
  • (7)
Cat. No. ABIN7208149
Quantity 100 μL
Datasheet Datasheet

Recommended PARP1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969442
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969441
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958679
Quantity 96 tests
Datasheet Datasheet

Recommended PARP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Baculovirus
Validations
  • (2)
  • (3)
Cat. No. ABIN1741729
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN5624620
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus
Validations
  • (1)
  • (2)
Cat. No. ABIN1741730
Quantity 5 μg
Datasheet Datasheet

Latest Publications for our PARP1 products

Wang, Liu, Wang, Gao, Li, Wu, Zhang, Wu, Kong, Yu, Yu: "Enhancing the antitumor activity of an engineered TRAIL-coated oncolytic adenovirus for treating acute myeloid leukemia." in: Signal transduction and targeted therapy, Vol. 5, Issue 1, pp. 40, (2020) (PubMed).

Cinque, Ferino, Pedersen, Xodo: "Role of Poly [ADP-ribose] Polymerase 1 in Activating the Kirstenras (KRAS) Gene in Response to Oxidative Stress." in: International journal of molecular sciences, Vol. 21, Issue 17, (2020) (PubMed).

Mega Tiber, Kocyigit Sevinc, Kilinc, Orun: "Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562." in: Gene, Vol. 692, pp. 217-222, (2019) (PubMed).

Takino, Sato, Nagamine, Hori: "The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells." in: Scientific reports, Vol. 9, Issue 1, pp. 16717, (2019) (PubMed).

Bera, Chiu, Huang, Liang, Lee, Shih: "Genetic and Epigenetic Perturbations by DNMT3A-R882 Mutants Impaired Apoptosis through Augmentation of PRDX2 in Myeloid Leukemia Cells." in: Neoplasia (New York, N.Y.), Vol. 20, Issue 11, pp. 1106-1120, (2019) (PubMed).

Dominguez, Maddelein, Pucelle, Nicaise, Maurage, Duyckaerts, Cuvillier, Delisle: "Neuronal sphingosine kinase 2 subcellular localization is altered in Alzheimer's disease brain." in: Acta neuropathologica communications, Vol. 6, Issue 1, pp. 25, (2019) (PubMed).

Li, Chen, Chen, Yen, Fang, Tsai, Chang, Shen, Huang, Chuu, Chang, Hsiung, Jiang: "Upregulation of CISD2 augments ROS homeostasis and contributes to tumorigenesis and poor prognosis of lung adenocarcinoma." in: Scientific reports, Vol. 7, Issue 1, pp. 11893, (2019) (PubMed).

Liu, Geng, Zhang, Wang, Zhang, Duan, Zhang: "Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway." in: Marine drugs, Vol. 16, Issue 3, (2018) (PubMed).

Dou, Li, Hu, Ding, Ma, Ma, Chai, Song: "Glutathione disulfide sensitizes hepatocytes to TNFα-mediated cytotoxicity via IKK-β S-glutathionylation: a potential mechanism underlying non-alcoholic fatty liver disease." in: Experimental & molecular medicine, Vol. 50, Issue 4, pp. 7, (2018) (PubMed).

Liu, Yang, Mu, Fu: "Epigallocatechin-3-Gallate Ameliorates Glucocorticoid-Induced Osteoporosis of Rats in Vivo and in Vitro." in: Frontiers in pharmacology, Vol. 9, pp. 447, (2018) (PubMed).

Synonyms and alternative names related to PARP1

poly(ADP-ribose) polymerase 1 (PARP1), poly (ADP-ribose) polymerase 1 (Parp1), poly (ADP-ribose) polymerase family, member 1 (Parp1), Poly-(ADP-ribose) polymerase (Parp), poly(ADP-ribose) polymerase 1 L homeolog (parp1.L), poly (ADP-ribose) polymerase 1 (PARP1), poly(ADP-ribose) polymerase 1 (Parp1), poly (ADP-ribose) polymerase 1 (parp1), 5830444G22Rik, Adprp, ADPRT, Adprt, ADPRT 1, ADPRT1, Adprt1, adprt1, AI893648, ARTD1, BEST:LD21673, C80510, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, dPARP, LD21673.3prime, pADPRT-1, padprt-1, PARP, parp, PARP-1, Parp-1, parp-1, PARP1, PPOL, ppol, si:dkey-206f10.3, sPARP-1, wu:fc60f12, zgc:110092

Protein level used designations for PARP1

  • ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)
  • ADP-ribosyltransferase NAD(+)
  • ADP-ribosyltransferase diphtheria toxin-like 1
  • NAD(+) ADP-ribosyltransferase 1
  • poly (ADP-ribose) polymerase family, member 1
  • poly [ADP-ribose] polymerase 1
  • poly(ADP-ribose) polymerase
  • poly(ADP-ribose) synthetase
  • poly(ADP-ribosyl)transferase
  • poly[ADP-ribose] synthase 1
  • ADP-ribosyltransferase (NAD+
  • ADP-ribosyltransferase 1
  • ADPRT 1
  • poly (ADP-ribose) polymerase)
  • poly(ADP-ribose) polymerase PARP-1
  • poly[ADP-ribose] synthetase 1
  • ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1
  • ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1
  • msPARP
  • CG40411-PB
  • CG40411-PC
  • Parp-PB
  • Parp-PC
  • Poly(ADP ribose) polymerase 1
  • Poly(ADP)-Ribose polymerase
  • Poly(ADP-)Ribose polymerase
  • Poly(ADP-ribose) polymerase
  • Poly(ADP-ribose) polymerase 1
  • PARP-1
  • ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase)
  • Poly[ADP-ribose] synthase 1
  • LOW QUALITY PROTEIN: poly [ADP-ribose] polymerase 1
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