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PARG1 Products

(rho GTPase Activating Protein 29 (ARHGAP29))

Categories

GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho (By similarity). In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis (By similarity).

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Featured PARG1 Categories

PARG1 Antibodies

High quality antibodies with extensive validation data.

PARG1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

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Latest Publications for our PARG1 products

Xu, Duan, Gan, Liu, Chen, Shen, Tang, Wang: "MicroRNA-1291 promotes endometrial fibrosis by regulating the ArhGAP29-RhoA/ROCK1 signaling pathway in a murine model." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 4501-4510, (2018) (PubMed).

Paul, Palmer, Sharp, Pratt, Murray, Dunnwald: "ARHGAP29 Mutation Is Associated with Abnormal Oral Epithelial Adhesions." in: Journal of dental research, Vol. 96, Issue 11, pp. 1298-1305, (2017) (PubMed).

Post, Pannekoek, Ponsioen, Vliem, Bos: "Rap1 Spatially Controls ArhGAP29 To Inhibit Rho Signaling during Endothelial Barrier Regulation." in: Molecular and cellular biology, Vol. 35, Issue 14, pp. 2495-502, (2015) (PubMed).

Biggs, Naridze, DeMali, Lusche, Kuhl, Soll, Schutte, Dunnwald: "Interferon regulatory factor 6 regulates keratinocyte migration." in: Journal of cell science, Vol. 127, Issue Pt 13, pp. 2840-8, (2014) (PubMed).

Post, Pannekoek, Ross, Verlaan, Brouwer, Bos: "Rasip1 mediates Rap1 regulation of Rho in endothelial barrier function through ArhGAP29." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 28, pp. 11427-32, (2013) (PubMed).

Leslie, Mansilla, Biggs, Schuette, Bullard, Cooper, Dunnwald, Lidral, Marazita, Beaty, Murray: "Expression and mutation analyses implicate ARHGAP29 as the etiologic gene for the cleft lip with or without cleft palate locus identified by genome-wide association on chromosome 1p22." in: Birth defects research. Part A, Clinical and molecular teratology, Vol. 94, Issue 11, pp. 934-42, (2012) (PubMed).

Synonyms and alternative names related to PARG1

Rho GTPase activating protein 29 (ARHGAP29), Rho GTPase activating protein 29b (arhgap29b), Rho GTPase activating protein 29 S homeolog (arhgap29.S), Rho GTPase activating protein 29 (arhgap29), Rho GTPase activating protein 29 (Arhgap29), 6720461J18Rik, A830014I19, arhgap29, ARHGAP29, AU040217, B130017I01Rik, B130017i01rik, C76601, PARG1, Parg1, RGD1306185, RP11-255E17.1, sb:cb905, zgc:63950

Protein level used designations for PARG1

  • Rho GTPase activating protein 29
  • rho GTPase-activating protein 29
  • rho-type GTPase-activating protein 29
  • PTPL1-associated RhoGAP 1
  • rho GTPase-activating protein 29-like
  • PTPL1-associated RhoGAP 1 (PARG1)
  • PTPL1-associated RhoGAP protein 1
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