PARD6A Products
(Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))
Categories
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Featured PARD6A Categories
PARD6A Antibodies
High quality antibodies with extensive validation data.
PARD6A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PARD6A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, FACS
Validations
- (3)
Cat. No.
ABIN185152
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN526360
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IF
Validations
- (2)
Cat. No.
ABIN7162663
Quantity
100 μg
Datasheet
Datasheet
Recommended PARD6A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313999
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314001
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3085394
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PARD6A products
: "Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier." in: Nature communications, Vol. 7, pp. 11876, (2016) (PubMed).: "Actin-interacting protein 1 controls assembly and permeability of intestinal epithelial apical junctions." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 308, Issue 9, pp. G745-56, (2015) (PubMed).
: "The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1." in: Journal of cell science, Vol. 113 ( Pt 18), pp. 3267-75, (2000) (PubMed).
Synonyms and alternative names related to PARD6A
par-6 partitioning defective 6 homolog alpha (C. elegans) (PARD6A), par-6 family cell polarity regulator alpha (PARD6A), par-6 family cell polarity regulator alpha (Pard6a), Partitioning defective protein 6 (par-6), 0710008C04Rik, 2610010A15Rik, Par-6, Par-6a, PAR-6A, Par6, PAR6, Par6a, PAR6alpha, Par6c, PAR6C, PARD6A, TAX40, Tip-40, TIP-40Protein level used designations for PARD6A
- par-6 partitioning defective 6 homolog alpha (C. elegans)
- partitioning defective 6 homolog alpha
- PAR-6 alpha
- PAR-6A
- Tax interaction protein 40
- partitioning defective protein 6A
- Tax-interacting protein 40
- par-6 partitioning defective 6 homolog alpha
- partitioning defective-6 homolog alpha
- partitioning-defective protein 6
- tax interaction protein 40
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