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PAR1 Products

(Coagulation Factor II (thrombin) Receptor (F2R))

Categories

Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. [provided by RefSeq, Jul 2008].

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Featured PAR1 Categories

PAR1 Antibodies

High quality antibodies with extensive validation data.

PAR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PAR1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PAR1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (5)
  • (4)
Cat. No. ABIN728743
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, ICC, IF
Validations
  • (2)
  • (3)
Cat. No. ABIN6265563
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (4)
Cat. No. ABIN5611342
Quantity 100 μL
Datasheet Datasheet

Recommended PAR1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954856
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965877
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965876
Quantity 96 tests
Datasheet Datasheet

Recommended PAR1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353311
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7407505
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7407502
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PAR1 products

Komori, Ago, Wakisaka, Nakamura, Tachibana, Yoshikawa, Shibahara, Yamanaka, Kuroda, Kitazono: "Early initiation of a factor Xa inhibitor can attenuate tissue repair and neurorestoration after middle cerebral artery occlusion." in: Brain research, Vol. 1718, pp. 201-211, (2019) (PubMed).

Posthuma, Posma, Schep, Bender, van Oerle, van der Wal, Ten Cate, Spronk: "Protease-activated receptors are potential regulators in the development of arterial endofibrosis in high-performance athletes." in: Journal of vascular surgery, Vol. 69, Issue 4, pp. 1243-1250, (2019) (PubMed).

Avril, Benjamin, Dols, Smith: "Interplay of Plasmodium falciparum and thrombin in brain endothelial barrier disruption." in: Scientific reports, Vol. 9, Issue 1, pp. 13142, (2019) (PubMed).

Zhao, Zheng, Liu, Luo, Wu, Liu, Zou: "Inhibiting trophoblast PAR-1 overexpression suppresses sFlt-1-induced anti-angiogenesis and abnormal vascular remodeling: a possible therapeutic approach for preeclampsia." in: Molecular human reproduction, Vol. 24, Issue 3, pp. 158-169, (2018) (PubMed).

Altieri, Bertolotto, Fabbi, Sportelli, Balbi, Santini, Brunelli, Canepa, Montecucco, Ameri: "Data regarding the effects of thrombin and dabigatran-inhibited thrombin on protease-activated receptor 1 and activation of human atrial fibroblasts." in: Data in brief, Vol. 19, pp. 925-931, (2018) (PubMed).

Choi, Yoon, Drucker, Langley, Kleppe, Scarisbrick: "The Thrombin Receptor Restricts Subventricular Zone Neural Stem Cell Expansion and Differentiation." in: Scientific reports, Vol. 8, Issue 1, pp. 9360, (2018) (PubMed).

Ben Shimon, Zeimer, Shavit Stein, Artan-Furman, Harnof, Chapman, Eisenkraft, Pick, Maggio: "Recovery from trauma induced amnesia correlates with normalization of thrombin activity in the mouse hippocampus." in: PLoS ONE, Vol. 12, Issue 11, pp. e0188524, (2017) (PubMed).

Zhong, Chen, Zhang, Xiao, Qin, Gu, Sun, Liu, Jing, Hu, Zhang, Zhou, Sun, Yang: "Doxycycline directly targets PAR1 to suppress tumor progression." in: Oncotarget, Vol. 8, Issue 10, pp. 16829-16842, (2017) (PubMed).

Antoniak, Tatsumi, Bode, Vanja, Williams, Mackman: "Protease-Activated Receptor 1 Enhances Poly I:C Induction of the Antiviral Response in Macrophages and Mice." in: Journal of innate immunity, Vol. 9, Issue 2, pp. 181-192, (2017) (PubMed).

Alvarez-Arce, Lee-Rivera, López, Hernández-Cruz, López-Colomé: "Thrombin-Induced Calpain Activation Promotes Protease-Activated Receptor 1 Internalization." in: International journal of cell biology, Vol. 2017, pp. 1908310, (2017) (PubMed).

Synonyms and alternative names related to PAR1

coagulation factor II thrombin receptor (F2R), coagulation factor II (thrombin) receptor (F2r), coagulation factor 2 (thrombin) receptor L homeolog (f2r.L), coagulation factor II thrombin receptor (F2r), AI482343, CF2R, Cf2r, f2r-a, HTR, PAR-1, Par-1, PAR1, Par1, par1, ThrR, TR, TRGPC

Protein level used designations for PAR1

  • protease-activated receptor 1
  • proteinase-activated receptor 1
  • PAR-1
  • Thrombin receptor
  • coagulation factor II receptor
  • thrombin receptor
  • protease-activated receptor-1
  • coagulation factor II (thrombin) receptor
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