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PAPSS2 Products

(3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2))

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Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Featured PAPSS2 Categories

PAPSS2 Antibodies

High quality antibodies with extensive validation data.

PAPSS2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PAPSS2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF, RNAi
Validations
  • (1)
  • (8)
Cat. No. ABIN563924
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (1)
  • (5)
Cat. No. ABIN2783448
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF
Validations
  • (4)
Cat. No. ABIN522499
Quantity 50 μg
Datasheet Datasheet

Recommended PAPSS2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6201022
Quantity 96 tests
Datasheet Datasheet

Recommended PAPSS2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313980
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313982
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3132103
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PAPSS2 products

Wang, Li, Wang, Cheng, Guo: "PAPSS2 promotes alkaline phosphates activity and mineralization of osteoblastic MC3T3-E1 cells by crosstalk and Smads signal pathways." in: PLoS ONE, Vol. 7, Issue 8, pp. e43475, (2012) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Venkatachalam: "Human 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase: biochemistry, molecular biology and genetic deficiency." in: IUBMB life, Vol. 55, Issue 1, pp. 1-11, (2003) (PubMed).

Xu, Otterness, Freimuth, Carlini, Wood, Mitchell, Moon, Kim, Xu, Siciliano, Weinshilboum: "Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1) and PAPSS2: gene cloning, characterization and chromosomal localization." in: Biochemical and biophysical research communications, Vol. 268, Issue 2, pp. 437-44, (2000) (PubMed).

Synonyms and alternative names related to PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2), 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (Papss2), 3'-phosphoadenosine 5'-phosphosulfate synthase 2b (papss2b), 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (papss2.S), 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (LOAG_05620), 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (papss2), 3'-phosphoadenosine 5'-phosphosulfate synthase 2a (papss2a), 1810018P12Rik, AI159688, ATPSK2, Atpsk2, AtpsU2, BCYM4, bm, id:ibd2761, Papss1, papss2, PAPSS2, sb:cb868, SK2, Sk2, wu:fb12e05, zgc:55851, zgc:85655, zgc:153748

Protein level used designations for PAPSS2

  • 3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 2
  • ATP sulfurylase/APS kinase 2
  • ATP sulfurylase/adenosine 5'-phosphosulfate kinase
  • PAPS synthase 2
  • PAPS synthetase 2
  • SK 2
  • bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2
  • bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2
  • PAPSS 2
  • brachymorphic
  • sulfurylase kinase 2
  • 3'-phosphoadenosine 5'-phosphosulfate synthase 2
  • adenosine 5'-phosphosulfate kinase/ATP sulfurylase 2
  • bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2-like
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