PAPPA Products
(Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
Categories
This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. [provided by RefSeq, Jul 2008].
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Featured PAPPA Categories
PAPPA Antibodies
High quality antibodies with extensive validation data.
PAPPA ELISA Kits
Reliable ELISA kits for a wide range of species.
PAPPA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PAPPA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, StM
Validations
- (4)
Cat. No.
ABIN6940248
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (3)
Cat. No.
ABIN718931
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC
Validations
- (3)
Cat. No.
ABIN7477551
Quantity
1 mL
Datasheet
Datasheet
Recommended PAPPA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969481
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958710
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958711
Quantity
96 tests
Datasheet
Datasheet
Recommended PAPPA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313974
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7411327
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7392137
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PAPPA products
: "Protein secretion is required for pregnancy-associated plasma protein-A to promote lung cancer growth in vivo." in: PLoS ONE, Vol. 7, Issue 11, pp. e48799, (2012) (PubMed).: "Point-of-care time-resolved immunofluorometric assay for human pregnancy-associated plasma protein A: use in first-trimester screening for Down syndrome." in: Clinical chemistry, Vol. 48, Issue 3, pp. 473-83, (2002) (PubMed).
Synonyms and alternative names related to PAPPA
pappalysin 1 (PAPPA), pregnancy-associated plasma protein A (Pappa), pappalysin 1 (Pappa1), pappalysin 1 (Pappa), 8430414N03Rik, ASBABP2, DIPLA1, IGFBP-4ase, PAG1, PAPA, PAPP-A, Pappa, PAPPA1Protein level used designations for PAPPA
- IGF-dependent IGFBP-4 protease
- insulin-like growth factor-dependent IGF-binding protein 4 protease
- pappalysin-1
- aspecific BCL2 ARE-binding protein 2
- differentially placenta 1 expressed protein
- insulin-like growth factor-dependent IGF binding protein-4 protease
- pregnacy-associated plasma protein A
- PAPPA-like protein
- pregnancy-associated plasma protein A-like protein
- cleaves insulin-like binding protein-4 (IGFBP-4)
- metalloprotease
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