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PAPOLG Products

(Poly(A) Polymerase gamma (PAPOLG))

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This gene encodes a member of the poly(A) polymerase family which catalyzes template-independent extension of the 3' end of a DNA/RNA strand. This enzyme shares 60% identity to the well characterized poly(A) polymerase II (PAPII) at the amino acid level. These two enzymes have similar organization of structural and functional domains. This enzyme is exclusively localized in the nucleus and exhibits both nonspecific and CPSF (cleavage and polyadenylation specificity factor)/AAUAAA-dependent polyadenylation activity. This gene is located on chromosome 2 in contrast to the PAPII gene, which is located on chromosome 14. [provided by RefSeq, Jul 2008].

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Featured PAPOLG Categories

PAPOLG Antibodies

High quality antibodies with extensive validation data.

Recommended PAPOLG Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC
Validations
  • (4)
Cat. No. ABIN1714858
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN657107
Quantity 400 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6740704
Quantity 100 μL
Datasheet Datasheet

Recommended PAPOLG ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232983
Quantity 96 tests
Datasheet Datasheet

Recommended PAPOLG Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094490
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3123680
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PAPOLG products

Muniz, Davidson, West: "Poly(A) Polymerase and the Nuclear Poly(A) Binding Protein, PABPN1, Coordinate the Splicing and Degradation of a Subset of Human Pre-mRNAs." in: Molecular and cellular biology, Vol. 35, Issue 13, pp. 2218-30, (2015) (PubMed).

Bresson, Conrad: "The human nuclear poly(a)-binding protein promotes RNA hyperadenylation and decay." in: PLoS genetics, Vol. 9, Issue 10, pp. e1003893, (2013) (PubMed).

Synonyms and alternative names related to PAPOLG

poly(A) polymerase gamma (papolg), poly(A) polymerase gamma L homeolog (papolg.L), poly(A) polymerase gamma (PAPOLG), poly(A) polymerase gamma (Papolg), 9630006B20Rik, zgc:63762

Protein level used designations for PAPOLG

  • SRP 3'-adenylating protein
  • PAP-gamma
  • SRP RNA 3' adenylating enzyme/pap2
  • SRP RNA 3'-adenylating enzyme
  • neo-PAP
  • neo-poly(A) polymerase
  • nuclear poly(A) polymerase gamma
  • polynucleotide adenylyltransferase gamma
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