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PAK7 Products

(P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

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The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].

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Featured PAK7 Categories

PAK7 Antibodies

High quality antibodies with extensive validation data.

PAK7 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PAK7 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN392438
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA
Validations
  • (5)
Cat. No. ABIN3028909
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN657995
Quantity 400 μL
Datasheet Datasheet

Recommended PAK7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509061
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094438
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136334
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PAK7 products

Cotteret, Jaffer, Beeser, Chernoff: "p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD." in: Molecular and cellular biology, Vol. 23, Issue 16, pp. 5526-39, (2003) (PubMed).

Jaffer, Chernoff: "p21-activated kinases: three more join the Pak." in: The international journal of biochemistry & cell biology, Vol. 34, Issue 7, pp. 713-7, (2002) (PubMed).

Pandey, Dan, Kristiansen, Watanabe, Voldby, Kajikawa, Khosravi-Far, Blagoev, Mann: "Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain." in: Oncogene, Vol. 21, Issue 24, pp. 3939-48, (2002) (PubMed).

Dan, Nath, Liberto, Minden: "PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells." in: Molecular and cellular biology, Vol. 22, Issue 2, pp. 567-77, (2001) (PubMed).

Synonyms and alternative names related to PAK7

p21 (RAC1) activated kinase 5 (PAK5), p21 (RAC1) activated kinase 5 L homeolog (pak5.L), p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7), p21 (RAC1) activated kinase 7 (Pak7), 2900083L08Rik, 6430627N20, PAK-5, PAK-7, PAK5, pak5, Pak5

Protein level used designations for PAK7

  • PAK-5
  • PAK-7
  • p21(CDKN1A)-activated kinase 7
  • p21-activated kinase 5
  • p21-activated kinase 7
  • p21CDKN1A-activated kinase 7
  • protein kinase PAK5
  • serine/threonine-protein kinase PAK 7
  • serine/threonine-protein kinase PAK7
  • p21 (CDKN1A)-activated kinase 7
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