PAK3 Products
(PAK3)
Categories
PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Featured PAK3 Categories
PAK3 Antibodies
High quality antibodies with extensive validation data.
PAK3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PAK3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (4)
Cat. No.
ABIN518612
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (4)
Cat. No.
ABIN5611206
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (5)
Cat. No.
ABIN3028914
Quantity
0.4 mL
Datasheet
Datasheet
Recommended PAK3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380787
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended PAK3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313925
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7317075
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
Cat. No.
ABIN5509220
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PAK3 products
: "P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153312, (2016) (PubMed).: "A 14-3-3? dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIII? to regulate post-Golgi carrier formation." in: Nature cell biology, Vol. 14, Issue 4, pp. 343-54, (2012) (PubMed).
: "Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees." in: Molecular biology and evolution, Vol. 20, Issue 8, pp. 1281-9, (2003) (PubMed).
Synonyms and alternative names related to PAK3
p21 (RAC1) activated kinase 3 (PAK3), p21 protein (Cdc42/Rac)-activated kinase 3 (Pak3), p21 (RAC1) activated kinase 3 (Pak3), p21 protein (Cdc42/Rac)-activated kinase 3 L homeolog (pak3.L), beta-PAK, bPAK, bpak, CDKN1A, cdkn1a, hPAK3, MRX30, mrx30, MRX47, mrx47, OPHN3, ophn3, PAK-3, pak3, pak3-A, PAK3beta, pak3beta, Pak65alpha, Pak65beta, Stk4, XPak3Protein level used designations for PAK3
- PAK-3
- beta-PAK
- oligophrenin-3
- p21 (CDKN1A)-activated kinase 3
- p21-activated kinase 3
- serine/threonine-protein kinase PAK 3
- CDC42/RAC effector kinase PAK-B
- p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related)
- p65-PAK
- PAK3a protein
- PAK3d protein
- serine/threonine protein kinase (p21-activated kinase 3)
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