Paired Box Gene 2a Products
(Paired Box Gene 2a (PAX2A))
Categories
PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008].
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Featured Paired Box Gene 2a Categories
Paired Box Gene 2a Antibodies
High quality antibodies with extensive validation data.
Paired Box Gene 2a Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Paired Box Gene 2a Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, Coat, StM
Validations
- (5)
Cat. No.
ABIN6940252
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (3)
- (4)
Cat. No.
ABIN562109
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN7193593
Quantity
100 μL
Datasheet
Datasheet
Recommended Paired Box Gene 2a ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6231710
Quantity
96 tests
Datasheet
Datasheet
Recommended Paired Box Gene 2a Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314063
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314062
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2131041
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Paired Box Gene 2a products
: "Matrine suppresses the migration and invasion of NSCLC cells by inhibiting PAX2-induced epithelial-mesenchymal transition." in: OncoTargets and therapy, Vol. 10, pp. 5209-5217, (2017) (PubMed).: "Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture." in: Nature, Vol. 500, Issue 7461, pp. 217-21, (2013) (PubMed).
: "Cerebral organoids model human brain development and microcephaly." in: Nature, Vol. 501, Issue 7467, pp. 373-9, (2013) (PubMed).
: "Expression of steroid receptor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance." in: British journal of cancer, Vol. 108, Issue 10, pp. 2039-44, (2013) (PubMed).
: "c-Jun is essential for the induction of Il-1? gene expression in in vitro activated Bergmann glial cells." in: Glia, Vol. 59, Issue 12, pp. 1879-90, (2012) (PubMed).
: "Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development." in: Human molecular genetics, Vol. 21, Issue 10, pp. 2357-69, (2012) (PubMed).
: "The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma." in: Carcinogenesis, Vol. 32, Issue 11, pp. 1713-23, (2011) (PubMed).
: "PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells." in: PLoS ONE, Vol. 6, Issue 8, pp. e22312, (2011) (PubMed).
: "Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells." in: Nature neuroscience, Vol. 13, Issue 10, pp. 1171-80, (2010) (PubMed).
: "Reactivation of optic nerve head astrocytes by TGF-beta2 and H2O2 is accompanied by increased Hsp32 and Hsp47 expression." in: Investigative ophthalmology & visual science, Vol. 50, Issue 4, pp. 1707-17, (2009) (PubMed).
Synonyms and alternative names related to Paired Box Gene 2a
paired box 2 (PAX2), paired box 2 (Pax2), paired box 2 L homeolog (pax2.L), paired box 2a (pax2a), paired box 2b (pax2b), cb378, noi, Opdc, PAPRS, Pax-2, pax-2, Pax-2a, pax-b, pax2, pax2.1, pax2.2, pax2a1, paxb, PAXZF-B, pax[zf-b], XPax-2, xPax-2a, XPax2Protein level used designations for Paired Box Gene 2a
- paired box homeotic gene 2
- paired box protein Pax-2
- optic disc coloboma
- paired box gene 2
- paired box protein Pax-2-A
- no isthmus protein
- paired box gene 2.1
- paired box homeotic gene 2a
- paired box protein Pax-2a
- paired box 2b
- paired box gene 2b
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