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Paired Box 3 Products

(Paired Box 3 (PAX3))

Categories

This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2\;13)(q35\;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008].

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Featured Paired Box 3 Categories

Paired Box 3 Antibodies

High quality antibodies with extensive validation data.

Paired Box 3 ELISA Kits

Reliable ELISA kits for a wide range of species.

Paired Box 3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Paired Box 3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (4)
  • (4)
Cat. No. ABIN737616
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
  • (4)
Cat. No. ABIN185216
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (4)
Cat. No. ABIN1724816
Quantity 100 μL
Datasheet Datasheet

Recommended Paired Box 3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884095
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384891
Quantity 96 tests
Datasheet Datasheet

Recommended Paired Box 3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314065
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314067
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3085795
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Paired Box 3 products

Dong, Yang, Fan, Ji, Zhang, Liu, Hu, Xie, Liu, Gao, Wang, Yao, Smith, Herrid: "Functional Role of Cyclin-Dependent Kinase 5 in the Regulation of Melanogenesis and Epidermal Structure." in: Scientific reports, Vol. 7, Issue 1, pp. 13783, (2017) (PubMed).

Li, Qiu, Liu, Wang, Hu, Gan, Wang: "Long-term thermal manipulation in the late incubation period can inhibit breast muscle development by activating endoplasmic reticulum stress in duck (Anasplatyrhynchos domestica)." in: Journal of thermal biology, Vol. 70, Issue Pt B, pp. 37-45, (2017) (PubMed).

Sahakyan, Pozzo, Duelen, Deprest, Sampaolesi: "Methotrexate and Valproic Acid Affect Early Neurogenesis of Human Amniotic Fluid Stem Cells from Myelomeningocele." in: Stem cells international, Vol. 2017, pp. 6101609, (2017) (PubMed).

Cao, Du, Lv, Lin, Mao, Xu, Liu, Liu: "PAX3 inhibits β-Tubulin-III expression and neuronal differentiation of neural stem cell." in: Biochemical and biophysical research communications, Vol. 485, Issue 2, pp. 307-311, (2017) (PubMed).

Rooper, Huang, Antonescu, Westra, Bishop: "Biphenotypic sinonasal sarcoma: an expanded immunoprofile including consistent nuclear β-catenin positivity and absence of SOX10 expression." in: Human pathology, Vol. 55, pp. 44-50, (2016) (PubMed).

Arts, Cané, Hennequart, Lamy, Bommer, Van den Eynde, De Plaen: "microRNA-155, induced by interleukin-1ß, represses the expression of microphthalmia-associated transcription factor (MITF-M) in melanoma cells." in: PLoS ONE, Vol. 10, Issue 4, pp. e0122517, (2015) (PubMed).

Bonchak, Eby, Willenborg, Chrobak, Henning, Krzywiec, Johnson, Le Poole: "Targeting melanocyte and melanoma stem cells by 8-hydroxy-2-dipropylaminotetralin." in: Archives of biochemistry and biophysics, Vol. 563, pp. 71-8, (2014) (PubMed).

Plouhinec, Roche, Pegoraro, Figueiredo, Maczkowiak, Brunet, Milet, Vert, Pollet, Harland, Monsoro-Burq: "Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers." in: Developmental biology, Vol. 386, Issue 2, pp. 461-72, (2014) (PubMed).

Kikuchi, Hettmer, Aslam, Michalek, Laub, Wilky, Loeb, Rubin, Wagers, Keller: "Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma." in: PLoS genetics, Vol. 10, Issue 1, pp. e1004107, (2014) (PubMed).

Abraham, Nuñez-Álvarez, Hettmer, Carrió, Chen, Nishijo, Huang, Prajapati, Walker, Davis, Rebeles, Wiebush, McCleish, Hampton, Bjornson, Brack, Wagers, Rando, Capecchi, Marini, Ehler, Zarzabal, Goros et al.: "Lineage of origin in rhabdomyosarcoma informs pharmacological response. ..." in: Genes & development, Vol. 28, Issue 14, pp. 1578-91, (2014) (PubMed).

Synonyms and alternative names related to Paired Box 3

paired box 3 (PAX3), paired box 3 (pax3), paired box 3 L homeolog (pax3.L), paired box 3 (Pax3), paired box 3a (pax3a), cdhs, CDHS, hup2, HUP2, pax-3, Pax-3, PAX3, Pax3, pax3, pax3b, Sp, splotch, ws1, WS1, WS3, xpax3, xPax3-B, zgc:92547

Protein level used designations for Paired Box 3

  • paired box 3
  • paired box protein 3
  • paired box gene 3 (Waardenburg syndrome 1)
  • Paired-domain transcription factor Pax3
  • Waardenburg syndrome 1
  • paired box protein Pax-3
  • paired-box 3
  • paired box protein Pax-3-like
  • paired box 3 b
  • paired box protein Pax-3-B
  • paired-domain transcription factor Pax3-B
  • paired box gene 3
  • paired box homeotic gene 3
  • paired domain gene 3
  • paired domain gene HuP2
  • paired-box 3 protein
  • homeodomain protein PAX3
  • etID309899.2
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