PAI1 Products
(Plasminogen Activator Inhibitor 1 (SERPINE1))
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This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
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Featured PAI1 Categories
PAI1 Antibodies
High quality antibodies with extensive validation data.
PAI1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PAI1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PAI1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (2)
- (6)
Cat. No.
ABIN969566
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (9)
Cat. No.
ABIN7427915
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7431938
Quantity
100 μL
Datasheet
Datasheet
Recommended PAI1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6959417
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6962500
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6959418
Quantity
96 tests
Datasheet
Datasheet
Recommended PAI1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275401
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1319636
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124465
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our PAI1 products
: "Arctigenin alleviates TGF-β1-induced epithelial-mesenchymal transition and PAI-1 expression via AMPK/NF-κB pathway in peritoneal mesothelial cells." in: Biochemical and biophysical research communications, Vol. 520, Issue 2, pp. 413-419, (2020) (PubMed).: "Cardiovascular Risk Indices and Their Impact on Outcome in Patients with Hyperglycaemic Emergencies in a Nigerian Hospital." in: Journal of the National Medical Association, Vol. 112, Issue 1, pp. 28-35, (2020) (PubMed).
: "Swim exercise inhibits hemostatic abnormalities in a rat model of obesity and insulin resistance." in: Archives of physiology and biochemistry, Vol. 125, Issue 1, pp. 79-84, (2019) (PubMed).
: "Effects of Simulated Heat Wave and Ozone on High Fat Diet ApoE Deficient Mice." in: Biomedical and environmental sciences : BES, Vol. 31, Issue 10, pp. 757-768, (2019) (PubMed).
: "Achyranthes bidentata polypeptide k improves long-term neurological outcomes through reducing downstream microvascular thrombosis in experimental ischemic stroke." in: Brain research, Vol. 1706, pp. 166-176, (2019) (PubMed).
: "Low-Intensity Focused Ultrasound-Responsive Phase-Transitional Nanoparticles for Thrombolysis without Vascular Damage: A Synergistic Nonpharmaceutical Strategy." in: ACS nano, Vol. 13, Issue 3, pp. 3387-3403, (2019) (PubMed).
: "TDP-43 knockdown causes innate immune activation via protein kinase R in astrocytes." in: Neurobiology of disease, Vol. 132, pp. 104514, (2019) (PubMed).
: "Non-invasive detection of local tissue responses to predict pressure ulcer development in mouse models." in: Journal of tissue viability, (2019) (PubMed).
: "Anticoagulant and Antithrombotic Properties in Vitro and in Vivo of a Novel Sulfated Polysaccharide from Marine Green Alga Monostroma nitidum." in: Marine drugs, Vol. 17, Issue 4, (2019) (PubMed).
: "VHL status regulates transforming growth factor-β signaling pathways in renal cell carcinoma." in: Oncotarget, Vol. 9, Issue 23, pp. 16297-16310, (2018) (PubMed).
Synonyms and alternative names related to PAI1
serpin family E member 1 (SERPINE1), serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog (serpine1.L), serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (serpine1), serine (or cysteine) peptidase inhibitor, clade E, member 1 (Serpine1), serpin family E member 1 (Serpine1), PAI, PAI-1, PAI1, Pai1, PAI1A, Pai1aa, Planh, PLANH1, Planh1, RATPAI1A, SERPINE1, si:ch211-138a11.1Protein level used designations for PAI1
- endothelial plasminogen activator inhibitor
- plasminogen activator inhibitor 1
- serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- serpin E1
- serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- PAI 1
- serine (or cysteine) proteinase inhibitor, clade E, member 1
- putative plasminogen activator inhibitor-1
- chemokine CCL-C25s
- plasminogen activator inhibitor 1-like
- PAI
- Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI)
- nexin, plasminogen activator inhibitor type 1
- plasminogen activator inhibitor, type I
- PAI-1
- serine (or cysteine) peptidase inhibitor, clade E, member 1
- serine (or cysteine) proteinase inhibitor, member 1
- plasminogen activator inhibitor I
- plasminogen activator inhibitor type 1
- plasminogen activator inhibitor, type 1
- plasminogen activator inhibitor-1
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